Burmistrov Dmitriy E, Serov Dmitriy A, Simakin Aleksander V, Baimler Ilya V, Uvarov Oleg V, Gudkov Sergey V
Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, Russia.
Polymers (Basel). 2022 Nov 7;14(21):4764. doi: 10.3390/polym14214764.
The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix-a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on "liquid Teflon" containing various concentrations of nanoparticles (0.001-0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production.
通过表面造成的细菌污染问题对食品工业而言至关重要。在这方面，人们对基于纳米颗粒的新型涂层越来越感兴趣，这类涂层能够提供长期抗菌效果。氧化铝纳米颗粒因其可得性和良好的生物相容性，是此类涂层的理想选择。在本研究中，以聚四氟乙烯作为聚合物基体——一种具有优异机械性能和物理化学性能且无毒的聚合物，制备了一种含有氧化铝纳米颗粒的涂层。所获得的基于“液态特氟龙”且含有不同浓度纳米颗粒（0.001 - 0.1 wt%）的涂层可抑制细菌生长，并且在体外对动物细胞不表现出细胞毒性。此类涂层的设计目的不仅是提供抗菌表面效果，还能消除食品生产过程中不可避免出现的表面微损伤。
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