Instuto de Química Pontificia Universidad Católica de Valparaíso, Valparaiso, Chile.
Department of Microbiology & Immunology, Tulane School of Medicine, New Orleans, Louisiana, USA.
J Med Primatol. 2023 Apr;52(2):131-134. doi: 10.1111/jmp.12626. Epub 2022 Nov 15.
Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19.
在感染 SARS-CoV-2 的 Chlorocebus aethiops(非洲绿猴;AGM)的尿液和血浆中均检测到可溶尿激酶型纤溶酶原激活物受体(suPAR)的增加。这些数据表明,在 COVID-19 背景下,suPAR 水平升高可能与肾功能障碍和肾脏病理有关。