Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
Division of Nuclear Medicine, Radiotherapy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
BMJ Case Rep. 2022 Nov 24;15(11):e250853. doi: 10.1136/bcr-2022-250853.
The unobliterated portion of embryological thyroglossal duct may present as cystic swelling later in life and may contain functional thyroid follicles. This cyst requires excision along with the entire thyroglossal duct remnant and adjacent portion of hyoid bone. At times, the excised specimen could demonstrate a focus of carcinomatous change inside the cyst wall. Very rarely, this thyroglossal duct cyst carcinoma could be associated with malignancy of native thyroid gland. This case report illustrates an interesting case of synchronous carcinoma of thyroglossal duct cyst and native thyroid gland. It also sheds light on the controversies related to the pathophysiology of such association and the dilemmas surrounding the management of thyroglossal duct cyst carcinoma, with or without concurrent carcinoma of thyroid gland.
胚胎甲状舌管未被吸收的部分在以后的生活中可能会表现为囊性肿胀,并可能包含功能性甲状腺滤泡。这种囊肿需要连同整个甲状舌管残余物和舌骨的邻近部分一起切除。有时,切除的标本在囊肿壁内可能显示出癌性变化的焦点。非常罕见的情况下,这种甲状舌管囊肿癌可能与甲状腺原发恶性肿瘤有关。本病例报告说明了一个有趣的同时发生的甲状舌管囊肿和甲状腺原发癌的病例。它还阐明了与这种关联的病理生理学相关的争议,以及在是否伴有甲状腺腺癌的情况下处理甲状舌管囊肿癌所面临的困境。