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胫骨平台骨折中临床显著静脉血栓栓塞症的发生率及危险因素。

Incidence and risk factors of clinically important venous thromboembolism in tibial plateau fractures.

机构信息

Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, Xi'an, China.

Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.

出版信息

Sci Rep. 2022 Nov 23;12(1):20206. doi: 10.1038/s41598-022-24717-1.

Abstract

While there are multiple reports on venous thromboembolism (VTE) associated with several orthopedic procedures, the knowledge regarding incidence and risk factors of VTE in tibial plateau fractures is limited. This study aimed to investigate the incidence and risk factors of clinically important venous thromboembolism (CIVTE) in patients with tibial plateau fractures. All adult patients who underwent surgical treatment of tibia plateau fractures between 2003 and 2018 in our level 1 trauma center were included in the study. All patients suspected CIVTE were assessed by the ultrasonography and/or CT scan. Univariate and multivariate analysis were used to evaluate the association between potential risk factors and CIVTE Variables. Thirty-nine of 462 patients (8.4%) developed clinically important venous thromboembolism, in which pulmonary embolism (PE) and deep vein thrombosis (DVT) were observed in 18 (3.9%) and 21 (4.54%) patients, respectively. Male gender (OR 9.75; 95% CI 2.34-40.66), spine injury (OR 9.51; 95% CI 3.39-26.64), other extremity injury (OR 3.7; 95% CI 1.58-8.66), length of stay in ICU (OR 1.14; 95% CI 1.09-1.2) were all risk factors for CIVTE. The incidence of CIVTE in tibial plateau fracture was relatively high (8.4%); The male gender, spine injury, other extremity injury, length of stay in ICU were the independent risk factors.

摘要

虽然有多个关于与多种骨科手术相关的静脉血栓栓塞症(VTE)的报告,但有关胫骨平台骨折中 VTE 的发生率和危险因素的知识有限。本研究旨在探讨胫骨平台骨折患者中临床重要静脉血栓栓塞症(CIVTE)的发生率和危险因素。所有在我们的 1 级创伤中心接受胫骨平台骨折手术治疗的成年患者均纳入本研究。所有疑似 CIVTE 的患者均通过超声检查和/或 CT 扫描进行评估。采用单因素和多因素分析评估潜在危险因素与 CIVTE 变量之间的关系。462 例患者中有 39 例(8.4%)发生了临床重要静脉血栓栓塞症,其中肺栓塞(PE)和深静脉血栓形成(DVT)分别在 18 例(3.9%)和 21 例(4.54%)患者中观察到。男性(OR 9.75;95%CI 2.34-40.66)、脊柱损伤(OR 9.51;95%CI 3.39-26.64)、其他肢体损伤(OR 3.7;95%CI 1.58-8.66)、入住 ICU 时间(OR 1.14;95%CI 1.09-1.2)均为 CIVTE 的危险因素。胫骨平台骨折中 CIVTE 的发生率相对较高(8.4%);男性、脊柱损伤、其他肢体损伤、入住 ICU 时间是独立的危险因素。

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