通过电子给体-受体配合物实现芳基黄原酸酯和芳基二硫代氨基甲酸酯的可见光驱动合成。
Visible-Light-Driven Synthesis of Aryl Xanthates and Aryl Dithiocarbamates via an Electron Donor-Acceptor Complex.
机构信息
State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, People's Republic of China.
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300071, People's Republic of China.
出版信息
Org Lett. 2022 Dec 9;24(48):8895-8900. doi: 10.1021/acs.orglett.2c03736. Epub 2022 Nov 28.
Herein, we report a facile, efficient, and practical protocol that enables the preparation of aryl xanthates and aryl dithiocarbamates from functionalized dibenzothiophenium salts via a photoactivated electron donor-acceptor complex. This mild, metal-free method is operationally simple and has a broad substrate scope and potential utility for late-stage functionalization of natural products and pharmaceuticals. Finally, this method also has redefined the substrate scope and reaction pathway for the Leuckart thiophenol reaction.
本文报道了一种简便、高效、实用的方法，通过光激活电子给体-受体配合物，可从功能化二苯并噻吩𬭩盐制备芳基黄原酸酯和芳基二硫代氨基甲酸酯。该方法温和、无金属、操作简单，具有广泛的底物范围，在天然产物和药物的后期官能团化方面具有潜在的应用价值。此外，该方法还重新定义了 Leuckart 硫酚反应的底物范围和反应途径。
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