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一种简单的方法来分析电子烟产生的气溶胶中的痕量金属。

A simple approach to analysing trace metals in aerosols produced by e-cigarettes.

机构信息

Department of Electrical Engineering and Electronics, School of Electrical Engineering, Electronics and Computer Science, University of Liverpool, Merseyside, UK.

Department of Chemical and Forensic Sciences, School of Applied Sciences, University of Huddersfield, West Yorkshire, UK.

出版信息

Drug Test Anal. 2023 Oct;15(10):1084-1090. doi: 10.1002/dta.3416. Epub 2022 Dec 12.

Abstract

Electronic cigarettes are a relatively new alternative to cigarettes, which have been marketed as being safer for users than conventional cigarettes. However, they may still result in inhalation of potentially toxic or carcinogenic substances, including metals produced by the heating element. This study looked at the levels of trace metals being produced by different atomizers used in e-cigarettes using a sample introduction technique based on the collection of aerosols produced by e-cigarettes in nitric acid, using glass midget impingers. Collected metals were then identified using an inductively coupled plasma-mass spectrometer (ICP-MS), which allowed detection in the low ppb range. Results obtained showed considerable variation in the levels of metals between both manufacturers of atomizers and also between different batches of coils. This variation is likely to be even greater if the ability of users to customise some types of e-cigarettes is considered. Although there are limitations in terms of possible interferences from other metallic components in the e-cigarettes, the findings suggest the proposed method could be of use in investigating the risk of inhalation of toxic metals from e-cigarette use.

摘要

电子烟是一种相对较新的香烟替代品,被宣传为比传统香烟对使用者更安全。然而,它们仍然可能导致吸入潜在的有毒或致癌物质,包括由加热元件产生的金属。本研究使用基于在硝酸中收集电子烟产生的气溶胶的样品引入技术,研究了不同电子烟中使用的雾化器产生的痕量金属的水平,使用玻璃微型冲击瓶。收集的金属然后使用电感耦合等离子体质谱仪 (ICP-MS) 进行鉴定,允许在低 ppb 范围内进行检测。结果表明,雾化器的制造商之间以及不同批次的线圈之间的金属含量存在相当大的差异。如果考虑到用户对某些类型的电子烟进行自定义的能力,这种差异可能会更大。尽管从电子烟中吸入有毒金属的风险调查可能存在来自电子烟其他金属成分的干扰的限制,但研究结果表明,所提出的方法可能有助于调查从电子烟使用中吸入有毒金属的风险。

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