The National Center for Trauma and Emergency Medicine Research, Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel.
The Department of Emergency Management and Disaster Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Eur J Trauma Emerg Surg. 2023 Apr;49(2):1145-1156. doi: 10.1007/s00068-022-02182-9. Epub 2022 Dec 1.
To compare mortality among severe and critically injured patients who were directly admitted (DA) to level I trauma center (TCI) or level II trauma center (TCII) with those who were transferred to a TCI after being initially admitted to a TCII.
A cohort study of severe and critically injured patients (Injury Severity Score 16-75) hospitalized between 2010 and 2019 using data from the National Program for Trauma Registration. Multivariate logistic regression models estimated mortality risk, including stratified analyses.
Of the 27,131 hospitalizations, 9.5% were transfers, 60.1% were DA to TCI and 30.4% were DA to TCII. Children ages ≤ 17 years, Non-Jews (minority), critical injuries (ISS 25-75), head injuries (AIS ≥ 3) and fall injuries were significantly more frequent among transfers, compared with the DA groups. Evacuation by emergency medical services was less frequent among transfers. After accounting for possible confounders, transfers had a greater risk of in-hospital mortality [DA to TCI vs transfer, OR (95% CI) 0.61 (0.52-0.72); DA to TCII vs transfer, OR (95% CI) 0.78 (0.65-0.94)]. In stratified analyses, these mortality differences persisted among the sub-group of patients who sustained critical injuries, among the patients with non-penetrating injuries, among the elderly ages ≥ 65 year and during the first 2 weeks of hospitalization.
This study has intervention implications that should be directed primarily at prehospital triage and the inter-hospital transfer processes. In addition, there may be a need to optimize the capabilities of regional trauma systems along with continuous performance evaluations and actions as required.
比较直接收入一级创伤中心(TCI)或二级创伤中心(TCII)的严重和危重伤患者与最初收入 TCII 后转入 TCI 的患者的死亡率。
使用国家创伤登记处的数据,对 2010 年至 2019 年期间住院的严重和危重伤患者(损伤严重程度评分 16-75)进行队列研究。多变量逻辑回归模型估计了死亡率风险,包括分层分析。
在 27131 例住院患者中,9.5%为转院患者,60.1%为直接收入 TCI,30.4%为直接收入 TCII。与 DA 组相比,年龄≤17 岁的儿童、非犹太人(少数民族)、严重损伤(ISS 25-75)、头部损伤(AIS≥3)和坠落伤在转院患者中更为常见。转院患者中由紧急医疗服务(EMS)转院的情况较少。在考虑到可能的混杂因素后,转院患者的住院死亡率风险更高[直接收入 TCI 与转院相比,比值比(95%可信区间)为 0.61(0.52-0.72);直接收入 TCII 与转院相比,比值比(95%可信区间)为 0.78(0.65-0.94)]。在分层分析中,这些死亡率差异在严重损伤患者亚组、非穿透性损伤患者亚组、年龄≥65 岁的老年患者亚组和住院前两周内持续存在。
本研究具有干预意义,主要应针对院前分诊和医院间转院过程。此外,可能需要优化区域创伤系统的能力,并根据需要进行持续的绩效评估和行动。