Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, 76 Yanta West Road, Xi'an, 710061, China.
Department of Pharmacy, University of Huddersfield, Queensgate, England.
Bull World Health Organ. 2022 Dec 1;100(12):758-768. doi: 10.2471/BLT.22.288420. Epub 2022 Nov 2.
To assess the procurement of medicines to treat cancer in China.
We conducted a descriptive analysis of the national procurement data for 20 anti-cancer medicines in China from 2015 to 2020. We estimated the number of defined daily doses procured per year in three areas of China for essential medicines and medicines for targeted therapies. We adjusted the data by the number of cancer patients in each region for each year.
Between 2015 and 2020, the number of defined daily doses per patient decreased from 40.87 to 35.86 (-12.27%) for essential medicines, while the number increased from 0.85 to 12.52 (1381.15%) for target medicines. The procurement of three out of 10 essential medicines decreased, whereas procurement of all 10 targeted medicines increased. In 2020, the eastern area procured the most essential medicines (44.98 doses per patient) and targeted medicines (16.55 doses per patient), but had the smallest relative change in procurement of both essential medicines (-22.76%) and targeted medicines (978.16%). The central area had the largest increase in procurement of both essential medicines (9.64%; from 25.25 to 27.68 doses per patient) and targeted medicines (4587.81%; from 0.23 to 10.64 doses per patient).
Procurement of anti-cancer medicines varied across regions. Specific policies are needed at the national level to eliminate inequalities in access to these medicines. Two issues that need attention are the lower access to many essential anti-cancer medicines in some provinces and the increase in use of targeted medicines.
评估中国癌症治疗药物的采购情况。
我们对 2015 年至 2020 年中国 20 种抗癌药物的国家采购数据进行了描述性分析。我们估计了三个地区每年用于基本药物和靶向治疗药物的规定日剂量数。我们根据每年每个地区的癌症患者人数对数据进行了调整。
2015 年至 2020 年,每位患者的规定日剂量数从基本药物的 40.87 下降到 35.86(-12.27%),而靶向药物的规定日剂量数从 0.85 增加到 12.52(1381.15%)。十种基本药物中有三种的采购量减少,而十种靶向药物的采购量都增加了。2020 年,东部地区采购的基本药物(每位患者 44.98 剂)和靶向药物(每位患者 16.55 剂)最多,但基本药物(-22.76%)和靶向药物(978.16%)采购量的相对变化最小。中部地区基本药物(9.64%;从 25.25 增加到 27.68 剂/患者)和靶向药物(4587.81%;从 0.23 增加到 10.64 剂/患者)的采购量增幅最大。
抗癌药物的采购在各地区之间存在差异。国家层面需要制定具体政策,消除获得这些药物的不平等。需要关注的两个问题是,一些省份获得许多基本抗癌药物的机会较低,以及靶向药物使用的增加。