Parsons Christine E, Purves Kirstin L, Skelton Megan, Peel Alicia J, Davies Molly R, Rijsdijk Fruhling, Bristow Shannon, Eley Thalia C, Breen Gerome, Hirsch Colette R, Young Katherine S
Department of Clinical Medicine, Interacting Minds Center, Aarhus University, Aarhus, Denmark.
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK.
Psychol Med. 2023 Oct;53(14):6524-6534. doi: 10.1017/S0033291722003828. Epub 2022 Dec 5.
While studies from the start of the COVID-19 pandemic have described initial negative effects on mental health and exacerbating mental health inequalities, longer-term studies are only now emerging.
In total, 34 465 individuals in the UK completed online questionnaires and were re-contacted over the first 12 months of the pandemic. We used growth mixture modelling to identify trajectories of depression, anxiety and anhedonia symptoms using the 12-month data. We identified sociodemographic predictors of trajectory class membership using multinomial regression models.
Most participants had consistently low symptoms of depression or anxiety over the year of assessments (60%, 69% respectively), and a minority had consistently high symptoms (10%, 15%). We also identified participants who appeared to show improvements in symptoms as the pandemic progressed, and others who showed the opposite pattern, marked symptom worsening, until the second national lockdown. Unexpectedly, most participants showed stable low positive affect, indicating anhedonia, throughout the 12-month period. From regression analyses, younger age, reporting a previous mental health diagnosis, non-binary, or self-defined gender, and an unemployed or a student status were significantly associated with membership of the stable high symptom groups for depression and anxiety.
While most participants showed little change in their depression and anxiety symptoms across the first year of the pandemic, we highlight the divergent responses of subgroups of participants, who fared both better and worse around national lockdowns. We confirm that previously identified predictors of negative outcomes in the first months of the pandemic also predict negative outcomes over a 12-month period.
自新冠疫情开始以来,已有研究描述了其对心理健康的初步负面影响以及加剧的心理健康不平等现象,但长期研究直到现在才出现。
英国共有34465人完成了在线问卷,并在疫情的头12个月里再次接受了调查。我们使用增长混合模型,利用这12个月的数据来确定抑郁、焦虑和快感缺失症状的轨迹。我们使用多项回归模型确定轨迹类别成员的社会人口学预测因素。
在评估的一年中,大多数参与者的抑郁或焦虑症状一直较低(分别为60%和69%),少数参与者的症状一直较高(分别为10%和15%)。我们还确定了随着疫情发展症状似乎有所改善的参与者,以及其他呈现相反模式(症状明显恶化)的参与者,直到第二次全国封锁。出乎意料的是,在整个12个月期间,大多数参与者表现出稳定的低积极情绪,表明存在快感缺失。回归分析显示,年龄较小、曾有心理健康诊断记录、非二元性别或自我定义性别、失业或学生身份与抑郁和焦虑症状稳定高分组的成员身份显著相关。
虽然大多数参与者在疫情的第一年里抑郁和焦虑症状变化不大,但我们强调了不同亚组参与者的不同反应,他们在全国封锁期间的表现有好有坏。我们证实,在疫情最初几个月中确定的负面结果预测因素在12个月期间也能预测负面结果。