法国职业性哮喘的主要致病因子，2001-2018 年向国家职业疾病监测和预防网络（RNV3P）报告。
Main Causal Agents of Occupational Asthma in France, Reported to the National Network for Occupational Disease Vigilance and Prevention (RNV3P) 2001-2018.
机构信息
Occupational Diseases Centre, CHRU Morvan, 2 Avenue Foch, 29609 Brest Cedex 2, France.
ORPHY Laboratory, 6 Av V Le Gorgeu 29238 Brest Cedex, Occidental Brittany University Brest, France.
出版信息
Ann Work Expo Health. 2023 Mar 15;67(3):297-302. doi: 10.1093/annweh/wxac079.
OBJECTIVES
The definition of work-related Asthma (WRA) has changed in recent years and new etiologies and agents have been identified. The aim of this study is to describe the main causal agents of WRA in France in the period 2001-2018 in the main work sectors.
METHODS
Data were collected from the French national network of occupational health surveillance and prevention [Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P)], Data between 2001 and 2018 with at least a probable or certain association with one occupational agent, were included.
RESULTS
Work sectors with more cases OF WRA included personal service activities (10.6%), food industry (10.2%) and healthcare activities (7.6%). WRA cases were most frequently related to flour (10%), quaternary ammoniums compounds (5.3%), isocyanates (5.1%) and cleaning products (4.8%).
CONCLUSION
Occupational exposure to specific agents capable of causing WRA is still present, and four agents represent more than 25% of the cases. Actions to prevent respiratory exposure are still relevant.
目的
近年来，工作相关哮喘（WRA）的定义发生了变化，新的病因和致因剂已被确定。本研究的目的是描述 2001-2018 年法国主要工作领域中 WRA 的主要致病因子。
方法
数据来自法国职业健康监测和预防国家网络[Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P)]，纳入了 2001 年至 2018 年期间至少与一种职业致因剂有明确或可能关联的病例。
结果
WRA 病例较多的工作领域包括个人服务活动（10.6%）、食品工业（10.2%）和医疗保健活动（7.6%）。WRA 病例最常与面粉（10%）、季铵化合物（5.3%）、异氰酸酯（5.1%）和清洁产品（4.8%）有关。
结论
职业接触特定的致因剂仍然存在，导致 WRA 的四个致因剂占比超过 25%。预防呼吸道接触的措施仍然是相关的。
Zotero 插件