Suppr超能文献

真实世界中特应性皮炎成年患者的治疗模式和治疗获益:来自特应性皮炎患者满意度和未满足需求调查的结果。

Real-World Treatment Patterns and Treatment Benefits among Adult Patients with Atopic Dermatitis: Results from the Atopic Dermatitis Patient Satisfaction and Unmet Need Survey.

机构信息

University Medical Center, Hamburg-Eppendorf, Germany.

Humanitas University Medical School Dermatology Via Alessandro Manzoni, Rozzano, Italy.

出版信息

Acta Derm Venereol. 2022 Dec 7;102:adv00830. doi: 10.2340/actadv.v102.3932.

Abstract

Atopic dermatitis is a chronic inflammatory skin disorder associated with a heterogeneous presentation and considerable disease burden. Exploring atopic dermatitis treatment patterns and patient benefits could improve disease management and patients' quality of life. This study aimed to describe current and previous atopic dermatitis treatment patterns and patient benefits from those treatments to inform disease management. Data were collected in 10 countries. Adults (n = 1,988) with confirmed moderate-to-severe atopic dermatitis completed a web-based cross-sectional survey. Most patients (86.6%) had body surface area involvement <10%, and therapies used were topical (69.7%), systemic (28.1%), and biologics (2.3%). Most flares were managed by topical monotherapies (73.4%), even in patients with body surface area involvement ≥10%. Treatment expectations were met only partially, or not at all, in 75% of patients. Those with body surface area involvement ≥10% reported lower treatment satisfaction. Overall, this study highlights the unmet medical needs in atopic dermatitis management.

摘要

特应性皮炎是一种慢性炎症性皮肤疾病,其表现形式多样,疾病负担较大。探索特应性皮炎的治疗模式和患者获益情况,可以改善疾病管理并提高患者的生活质量。本研究旨在描述当前和既往特应性皮炎的治疗模式,以及患者从这些治疗中获益的情况,以为疾病管理提供信息。数据收集于 10 个国家。1988 名确诊为中重度特应性皮炎的成年患者完成了一项基于网络的横断面调查。大多数患者(86.6%)的体表面积受累<10%,所使用的治疗方法包括局部治疗(69.7%)、系统治疗(28.1%)和生物制剂(2.3%)。即使在体表面积受累≥10%的患者中,大多数(73.4%)患者的病情发作也通过局部单一疗法来管理。75%的患者仅部分或完全未能达到治疗预期。体表面积受累≥10%的患者治疗满意度更低。总的来说,本研究强调了特应性皮炎管理中存在的未满足的医疗需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc48/10508272/e7ff7927e1cb/ActaDV-102-3932-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验