Zarif Yussefian Nikta, Tanguay Jesse
Department of Physics, Toronto Metropolitan University, Toronto, ON, Canada.
Med Phys. 2023 Mar;50(3):1318-1335. doi: 10.1002/mp.16114. Epub 2023 Jan 11.
Assessing the performance of spectroscopic x-ray detectors (SXDs) requires measurement of the frequency-dependent detective quantum efficiency (DQE). Analytical expressions of the task-based DQE and task-independent DQE of SXDs have been presented in the literature, but standardizable experimental methods for measuring them have not. The task-based DQE quantifies the efficiency with which an SXD uses the x-ray quanta incident upon it to either quantify or detect a basis material (e.g., soft tissue or bone) of interest. The task-independent DQE is akin to the conventional DQE in that it is independent of the basis material to be detected or quantified.
The purpose of this paper is to develop an experimental framework to present a method for experimental analysis of the DQE of SXDs, including the task-based DQE and task-independent DQE.
We develop methods to measure the frequency-dependent DQE for task of quantifying or detecting a perturbation in a known basis material. We also develop methods for measuring a task-independent DQE. We show that the task-based DQEs and the task-independent DQE can be measured using a modest extension of the methods prescribed by International Electrotechnical Commission (IEC). Specifically, measuring the task-independent DQE requires measuring the modulation transfer function (MTF) and noise power spectrum (NPS) of each energy-bin image, in addition to the cross NPS between energy-bin images. Measuring the task-based DQEs requires an additional measurement of the transmission fraction through a thin basis-material absorber. We implemented the developed methods using standardized IEC x-ray spectra, aluminum (Al) and polymethyl methacrylyte (PMMA) basis materials, and a cadmium telluride (CdTe) SXD equipped with two energy bins and analog charge summing (ACS) for charge-sharing suppression. We also performed a regression analysis to determine whether or not the task-independent DQE is predictive of the task-based DQEs.
Experimental results of the task-based DQEs were consistent with simulation results presented in the literature. In general, and as expected, ACS increased the task-based DQEs and task-independent DQE. This effect was most pronounced for quantification tasks, in some instances yielding a five-fold increase in the DQE. For both spectra, with and without ACS for charge sharing correction, the task-based DQEs were linearly related to the task-independent DQE, as demonstrated by R -values ranging from 0.89 to 1.00.
We have extended experimental DQE analysis to SXDs that count photons in multiple energy bins in a single x-ray exposure. The developed framework is an extension of existing IEC methods, and provides a standardized approach to assessing the performance of SXDs.
评估光谱X射线探测器(SXD)的性能需要测量频率相关的探测量子效率(DQE)。文献中已给出了基于任务的DQE和与任务无关的DQE的解析表达式,但尚未有用于测量它们的标准化实验方法。基于任务的DQE量化了SXD利用入射X射线量子来量化或检测感兴趣的基础材料(如软组织或骨骼)的效率。与任务无关的DQE类似于传统的DQE,因为它与要检测或量化的基础材料无关。
本文的目的是开发一个实验框架,以提出一种对SXD的DQE进行实验分析的方法,包括基于任务的DQE和与任务无关的DQE。
我们开发了用于测量在已知基础材料中量化或检测扰动任务的频率相关DQE的方法。我们还开发了测量与任务无关的DQE的方法。我们表明,基于任务的DQE和与任务无关的DQE可以通过对国际电工委员会(IEC)规定的方法进行适度扩展来测量。具体而言,测量与任务无关的DQE除了要测量每个能量区间图像的调制传递函数(MTF)和噪声功率谱(NPS)外,还需要测量能量区间图像之间的交叉NPS。测量基于任务的DQE需要额外测量通过薄基础材料吸收体的透射分数。我们使用标准化的IEC X射线光谱、铝(Al)和聚甲基丙烯酸甲酯(PMMA)基础材料以及配备两个能量区间和用于电荷共享抑制的模拟电荷求和(ACS)的碲化镉(CdTe)SXD来实施所开发的方法。我们还进行了回归分析,以确定与任务无关的DQE是否可预测基于任务的DQE。
基于任务的DQE的实验结果与文献中给出的模拟结果一致。总体而言,正如预期的那样,ACS提高了基于任务的DQE和与任务无关的DQE。这种效应在量化任务中最为明显,在某些情况下,DQE提高了五倍。对于有无用于电荷共享校正的ACS的两种光谱,基于任务的DQE与与任务无关 的DQE呈线性相关,R值范围为0.89至1.00表明了这一点。
我们已将实验DQE分析扩展到在单次X射线曝光中对多个能量区间的光子进行计数的SXD。所开发的框架是现有IEC方法的扩展,并提供了一种评估SXD性能的标准化方法。