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钨橡胶推注在瘢痕疙瘩和浅表肿瘤光子放疗中对表面剂量的双重增强效应。

Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.

作者信息

Sakai Yusuke, Monzen Hajime, Tamura Mikoto, Nakamura Kenji, Nishimura Yasumasa

机构信息

Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, 377-2 Onohigashi, Osakasayama, Osaka, 589-8511, Japan.

Department of Radiotherapy, Takarazuka City Hospital, 4-5-1 Kohama, Takarazuka, Hyogo, 665-0827, Japan.

出版信息

Phys Eng Sci Med. 2023 Mar;46(1):179-184. doi: 10.1007/s13246-022-01208-1. Epub 2022 Dec 9.

Abstract

To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloids and other superficial tumors. A 5 mm gel bolus or 1 mm STR bolus was placed on a solid water phantom. Tangential irradiation was performed using a TomoTherapy Radixact-X9 and 6 MV X-ray flattening-filter-free beam, and the surface dose was measured with radiochromic film. Clinical-like plans (TomoDirect; TD and TomoHelical; TH) were applied with the same geometry and the dose distributions were measured. The increase in surface dose by the build-up effect and backscatter was 37.7% and 8.0% for the gel bolus, and 40.5% and 26.4% for the STR bolus, respectively. In the TD and TH plans, the increase in surface dose was 27.4% and 48.3% for the gel bolus, and 39.0% and 63.2% for the STR bolus. Similary, changes in the sagittal plane dose were - 3.9% and 6.1% for the gel bolus, and - 6.3% and 6.9% for the STR bolus. The STR bolus effectively increased the surface dose by the build-up effect and backscatter in photon radiotherapy for keloids and other superficial tumors.

摘要

为明确临床计划中实时可变形状含橡胶钨(STR) bolus的剂量学特征,并研究STR bolus在瘢痕疙瘩及其他浅表肿瘤光子放疗中的疗效。将5mm凝胶bolus或1mm STR bolus置于固体水模体上。使用螺旋断层放疗系统(TomoTherapy Radixact-X9)和6MV X射线无均整器光束进行切线照射,并用放射变色胶片测量表面剂量。应用类似临床的计划(TomoDirect;TD和TomoHelical;TH),保持相同几何形状并测量剂量分布。对于凝胶bolus,由于建成效应和反向散射导致的表面剂量增加分别为37.7%和8.0%,对于STR bolus则分别为40.5%和26.4%。在TD和TH计划中,凝胶bolus的表面剂量增加分别为27.4%和48.3%,STR bolus的表面剂量增加分别为39.0%和63.2%。同样,凝胶bolus矢状面剂量变化分别为-3.9%和6.1%,STR bolus矢状面剂量变化分别为-6.3%和6.9%。STR bolus在瘢痕疙瘩及其他浅表肿瘤的光子放疗中通过建成效应和反向散射有效增加了表面剂量。

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