Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Suite 3080, Philadelphia, PA, 19104-3309, USA.
Department of Genetics, Perelman School of Medicine, Clinical Research Building, 415 Curie Boulevard, University of Pennsylvania, Philadelphia, PA, 19104-6145, USA.
J Autism Dev Disord. 2024 Mar;54(3):1088-1100. doi: 10.1007/s10803-022-05822-6. Epub 2022 Dec 9.
There is uncertainty among researchers and clinicians about how to best measure autism spectrum dimensional traits in adults. In a sample of adults with high levels of autism spectrum traits and without intellectual disability (probands, n = 103) and their family members (n = 96), we sought to compare self vs. informant reports of autism spectrum-related traits and possible effects of sex on discrepancies. Using correlational analysis, we found poor agreement between self- and informant-report measures for probands, yet moderate agreement for family members. We found reporting discrepancy was greatest for female probands, often self-reporting more autism-related behaviors. Our findings suggest that autism spectrum traits are often underrecognized by informants, making self-report data important to collect in clinical and research settings.
研究人员和临床医生对于如何最好地衡量成人自闭症谱系多维特征存在不确定性。在一个具有高水平自闭症谱系特征且无智力障碍的成年人样本(先证者,n=103)及其家庭成员(n=96)中,我们试图比较自闭症谱系相关特征的自我报告与知情者报告,以及性别对差异的可能影响。使用相关分析,我们发现先证者的自我报告和知情者报告之间的一致性很差,但家庭成员之间的一致性中等。我们发现女性先证者的报告差异最大,她们通常自我报告更多的自闭症相关行为。我们的研究结果表明,自闭症谱系特征通常被知情者所忽视,因此在临床和研究环境中,自我报告数据非常重要。