Department of Epidemiology, Biostatistics and Evidence-Based Medicine, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.
Health Research Center, Asfendiyarov Kazakh National Medical University, Almaty 050000, Kazakhstan.
Int J Environ Res Public Health. 2022 Dec 3;19(23):16189. doi: 10.3390/ijerph192316189.
Cognitive impairment in older adults is a major public concern for Kazakhstan's aging population. We aimed to (1) administer a neuropsychological test battery (NTB) in domains relevant to aging-associated cognitive impairment in a sample of adults aged 60+ without dementia in Almaty, Kazakhstan; (2) investigate the associations between demographic factors and test performance; and (3) provide information on the distribution of NTB scores as preliminary local normative data relevant for this population. A cross-sectional evaluation of 276 participants aged 60+ in Almaty, Kazakhstan, was conducted using cognitive instruments including tests of memory, attention, language, executive functions, visuospatial abilities, and processing speed. Multiple linear regression analyses were used to examine the association of demographic factors with neuropsychological test performance. The results from the regression analysis showed that those who are younger, have more years of education, are women, and are of Russian ethnicity had significantly better performance. The current study illustrated (1) the feasibility of administering the NTB to older adults in the general population in Kazakhstan; (2) the preliminary local normative neuropsychological measures; and (3) their independent associations with age, education, gender, and ethnicity. The findings are a platform for future research on dementia and cognitive impairment in older adults in Kazakhstan.
认知障碍在老年人中是哈萨克斯坦老龄化人口的主要公众关注点。我们的目的是:(1)在阿拉木图的一组无痴呆的 60 岁以上成年人中进行与与衰老相关的认知障碍相关的神经心理学测试组合(NTB);(2)调查人口统计学因素与测试表现之间的关系;(3)提供 NTB 分数的分布信息作为该人群的初步本地规范数据。使用认知工具对 276 名年龄在 60 岁以上的阿拉木图参与者进行了横断面评估,包括记忆力、注意力、语言、执行功能、视空间能力和处理速度测试。多元线性回归分析用于检查人口统计学因素与神经心理学测试表现之间的关系。回归分析的结果表明,年龄较小、受教育年限较长、女性和俄罗斯族裔的参与者表现明显更好。本研究说明了:(1)在哈萨克斯坦普通人群中进行 NTB 测试的可行性;(2)初步的本地规范神经心理学测量;(3)它们与年龄、教育、性别和种族的独立关联。这些发现为未来在哈萨克斯坦开展老年人痴呆症和认知障碍的研究提供了平台。