Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Research Centre for Greenhouse Gas Innovation (RGCI-POLI-USP), University of São Paulo, São Paulo, Brazil.
Recent Pat Biotechnol. 2023;17(3):271-288. doi: 10.2174/1872208317666221207145011.
As global awareness regarding climate change and environmental pollution outcomes arise, eco-friendly and negative emission technologies emerge.
In this scenario, polyhydroxyalkanoate (PHA)-accumulating microorganisms play an important role in the transition from the petrochemical-based non-biodegradable polymer to renewable, eco-friendly, and biocompatible materials. More specifically, CO can be converted to biopolymers through photosynthesis by cyanobacteria and algae, posing as a promising technology for renewable material, CO, and petroleum-dependence mitigations. However, although many microorganisms can accumulate PHA intracellularly, limitations persist, such as the elevated cost and limited market availability.
Herein is presented a patent-based mapping on technological trends of PHAs production, including its production by microalgae and cyanobacteria using the Questel Orbit Intelligence software (version 1.9.8) in complement with the Espacenet Patent Search database.
The inquiry on PHAs retrieved 34,243 patents filed since 1912, whereas 156 are related to their specific production by photosynthetic microorganisms, evidencing a prospective market for intellectual property.
随着人们对气候变化和环境污染后果的全球意识的提高,环保和负排放技术应运而生。
在这种情况下,聚羟基脂肪酸酯(PHA)积累微生物在从基于石油的不可生物降解聚合物向可再生、环保和生物相容材料的转变中发挥着重要作用。更具体地说,通过蓝藻和藻类的光合作用,CO 可以转化为生物聚合物,这是一种有前途的可再生材料、CO 和石油依赖缓解技术。然而,尽管许多微生物可以在细胞内积累 PHA,但仍然存在一些限制,例如成本高和市场供应有限。
本研究基于专利的方法,利用 Questel Orbit Intelligence 软件(版本 1.9.8)和 Espacenet 专利搜索数据库,对 PHAs 生产的技术趋势进行了分析。
对 PHA 的查询检索到自 1912 年以来提交的 34243 项专利,其中 156 项与光合微生物的特定生产有关,这表明知识产权具有广阔的市场前景。