Neonakis Ioannis K, Skamagkas Iordanis, Stafylaki Dimitra, Maraki Sofia
MD, MSc, PhD, Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, Voutes, 71201 Heraklion, Greece.
MD, Department of Urology, University Hospital of Heraklion, Voutes, 71201 Heraklion, Greece.
Germs. 2022 Jun 30;12(2):304-307. doi: 10.18683/germs.2022.1333. eCollection 2022 Jun.
Lactobacilli are Gram-positive rods, commensals of the normal human flora. Generally, these lactic acid-producing bacteria are considered contaminants, however over the last years their clinical relevance is reevaluated. is very rarely isolated and only a few cases of urinary tract infections (UTIs) have been reported, mainly in females.
We report the case of a UTI in an 82-year-old male suffering from benign prostate hyperplasia with repeated episodes of acute urinary retention over the last month before presenting to our hospital. The catheter urine culture grew >10 CFUs/mL of pure on Columbia CNA blood agar and on Trypticase soy agar. Identification was achieved by matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS), using VITEK MS (bioMérieux, France). The patient was successfully treated with cefixime for ten days. A follow-up urine culture performed 7 days after antibiotic discontinuation was sterile.
To our knowledge the present is the second case of urinary tract infection in a male patient. Further cases are required to confirm the clinical significance of these unusual pathogens and their involvement in human urinary tract infections.
乳酸杆菌是革兰氏阳性杆菌,是人类正常菌群的共生菌。一般来说,这些产乳酸的细菌被视为污染物,然而在过去几年中,它们的临床相关性正在被重新评估。很少被分离出来,仅报告了少数几例其引起的尿路感染(UTI),主要发生在女性中。
我们报告了一例82岁男性尿路感染病例,该患者患有良性前列腺增生,在入院前的最后一个月内反复出现急性尿潴留。导尿管尿液培养在哥伦比亚CNA血琼脂和胰蛋白胨大豆琼脂上生长出>10 CFU/mL的纯[细菌名称未给出]。使用VITEK MS(法国生物梅里埃公司)通过基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)进行鉴定。患者用头孢克肟成功治疗了10天。抗生素停用7天后进行的随访尿液培养无菌。
据我们所知,本病例是男性患者中第二例[细菌名称未给出]引起的尿路感染。需要更多病例来证实这些不寻常病原体的临床意义及其在人类尿路感染中的作用。