Sadeghian Mahnaz, Vafadar Mehdi, Torabi Ala, Torabi Sara, Fazel Mehrshad
Associated Professor of Pediatric Gastroenterologist, Department of Pediatric, Ali Asghar Children's Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Assistant Professor of Pediatric Endocrinology, Department of Pediatric, Ali Asghar Children's Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
J Family Med Prim Care. 2022 Sep;11(9):5604-5608. doi: 10.4103/jfmpc.jfmpc_626_22. Epub 2022 Oct 14.
Fatty liver disease is a severe liver condition that affects youngsters. Liver disease in children increases the incidence of liver fibrosis in their adulthood. Due to the importance of this disease and related factors in children, such as diabetes and obesity, our study was conducted to investigate the prevalence of fatty liver in children.
This is a descriptive cross-sectional study done in Ali Asghar Hospital from June 2020 to December 2020. Demographic characteristics and prevalence of fatty liver were assessed. Blood samples were obtained after ten hours of fasting to assess AST, ALT, ALP, and blood glucose levels. Ultrasound was also used to check the health of the liver. Walking to school and exercising were also assessed. Data were analyzed using statistical software.
This research included 2526 children, and 37 of them had fatty liver. Fatty liver was more common in children with a BMI greater than 30, as well as metabolic and hypoparathyroid illness ( = 0.02). A significant association was observed between exercise and walking with fatty liver disease ( < 0.05). The majority of the individuals had grade 1 fatty liver (75.5%). Grade 1 fatty liver was seen in 90% of those who did not participate in athletics and 95% of those who did not walk to school. In addition, 94% of patients who exercised for less than ten minutes had grade 1fatty liver.
Initially, exercise and weight loss had an essential effect on fatty liver disease. In fact, lifestyle changes and prevention of obesity may reduce liver damage.
脂肪肝是一种影响青少年的严重肝脏疾病。儿童期肝病会增加其成年后患肝纤维化的几率。鉴于这种疾病以及糖尿病和肥胖等儿童相关因素的重要性,我们开展了这项研究来调查儿童脂肪肝的患病率。
这是一项于2020年6月至2020年12月在阿里·阿斯加尔医院进行的描述性横断面研究。评估了人口统计学特征和脂肪肝患病率。在禁食10小时后采集血样以评估谷草转氨酶(AST)、谷丙转氨酶(ALT)、碱性磷酸酶(ALP)和血糖水平。还使用超声检查肝脏健康状况。同时评估了步行上学和锻炼情况。使用统计软件对数据进行分析。
本研究纳入了2526名儿童,其中37名患有脂肪肝。脂肪肝在体重指数(BMI)大于30的儿童以及患有代谢和甲状旁腺功能减退疾病的儿童中更为常见(P = 0.02)。观察到锻炼和步行与脂肪肝疾病之间存在显著关联(P < 0.05)。大多数个体患有1级脂肪肝(75.5%)。未参加体育活动的儿童中90%患有1级脂肪肝,未步行上学的儿童中95%患有1级脂肪肝。此外,锻炼时间少于10分钟的患者中94%患有1级脂肪肝。
首先,锻炼和减肥对脂肪肝疾病有重要影响。事实上,改变生活方式和预防肥胖可能会减少肝脏损伤。