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接受抗血管内皮生长因子注射治疗早产儿视网膜病变的婴儿出现摇晃婴儿综合征。

Shaken baby syndrome in an infant treated for retinopathy of prematurity with anti-VEGF injection.

机构信息

Department of Ophthalmology, Dr Behcet Uz Pediatric Diseases and Surgery Training and Research Hospital, Izmir, Turkey.

Department of Ophthalmology, Dr Behcet Uz Pediatric Diseases and Surgery Training and Research Hospital, Izmir, Turkey.

出版信息

J AAPOS. 2023 Feb;27(1):42-44. doi: 10.1016/j.jaapos.2022.11.004. Epub 2022 Dec 12.

Abstract

We present the case of an infant who received bevacizumab treatment for retinopathy of prematurity (ROP) and developed retinal hemorrhages 12 weeks later. Although preretinal hemorrhages along the ROP's ridge were a concern for recurrence, we decided to investigate other etiologies because of numerous retinal hemorrhages in different retinal layers and their concentration in the posterior pole. Cranial magnetic resonance imaging revealed a new-onset subdural hemorrhage. Factors that were suspicious for trauma were identified in the detailed history taken from the family by the hospital's child abuse team. This case highlights the importance of considering the characteristics of retinal hemorrhages in infants with ROP and conducting any necessary investigation.

摘要

我们报告了一例婴儿接受贝伐单抗治疗早产儿视网膜病变(ROP),并在 12 周后出现视网膜出血。尽管沿 ROP 脊的视网膜前出血令人担心复发,但由于不同视网膜层出现大量视网膜出血且集中在后极部,我们决定调查其他病因。头颅磁共振成像显示新发硬膜下血肿。医院的儿童虐待小组通过向家庭详细询问病史,发现了疑似创伤的因素。该病例强调了在 ROP 婴儿中考虑视网膜出血特征并进行任何必要检查的重要性。

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