一组具有抗毒蕈碱活性的X-苄基三甲基铵衍生物的相关性分析。
Correlation analysis in a set of X-benzyltrimethylammonium derivatives with antimuscarinic activity.
作者信息
De Amici M, De Micheli C, Pratesi P, Grana E, Santagostino Barbone M G, Cappello B, Silipo C, Vittoria A
机构信息
Istituto di Chimica Farmaceutica, Università di Milano, Italy.
出版信息
Farmaco Sci. 1987 Jun;42(6):409-24.
PMID:3653389
Abstract
The results of a pharmacological investigation on a series of meta-substituted benzyltrimethylammonium salts possessing an antimuscarinic activity are reported. Correlative analysis shows that the pharmacodynamic activity is a function of the hydrophobic-lipophilic parameter associated with the substituent.
摘要
报道了对一系列具有抗毒蕈碱活性的间位取代苄基三甲基铵盐的药理学研究结果。相关分析表明，药效学活性是与取代基相关的疏水-亲脂性参数的函数。
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Correlation analysis in a set of X-benzyltrimethylammonium derivatives with antimuscarinic activity.一组具有抗毒蕈碱活性的X-苄基三甲基铵衍生物的相关性分析。
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