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全内脏转位伴胃腺癌:1例罕见病例

Adenocarcinoma of the Stomach With Situs Inversus Totalis: A Rare Case.

作者信息

Lamture Yashwant, Gharde Pankaj, Gajbhiye Varsha, Nagtode Tushar, Mastud Kiran, Kulkarni Varun, Patel Dhaval

机构信息

General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Pharmacology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2022 Nov 15;14(11):e31538. doi: 10.7759/cureus.31538. eCollection 2022 Nov.

Abstract

Situs inversus is a scarce congenital anomaly. Situs inversus totalis (SIT) is a mirroring of the normal. Thoracic and abdominal viscera transposition is a characteristic feature of situs inversus. It is considered to be a premalignant condition. This uncommon genetic disorder is often identified incidentally during thoracic and abdominal imaging. The coexistence of SIT and gastric cancer is rare. Because this anomaly is known to have associated anatomical and vascular anomalies, due care is required to identify it preoperatively and during the surgical procedure. At centers with prior experience, consistent with oncological practices, open surgeries, laparoscopic surgeries, and robotic surgeries can be done. We present a patient with a stomach adenocarcinoma with SIT who underwent distal gastrectomy with gastrojejunostomy along with resection and anastomosis of the transverse colon and capecitabin-oxaliplatin chemotherapy. The postoperative course was favorable. To our knowledge, only 13 cases of diffuse-type gastric cancer in a patient with SIT have been reported in the English-language literature.

摘要

内脏反位是一种罕见的先天性异常。全内脏反位(SIT)是正常情况的镜像。胸腹部脏器转位是内脏反位的特征性表现。它被认为是一种癌前状态。这种罕见的遗传性疾病常在胸腹部影像学检查时偶然发现。SIT与胃癌并存的情况很少见。由于已知这种异常伴有相关的解剖和血管异常,因此在术前和手术过程中需要格外小心以识别它。在有经验的中心,按照肿瘤学实践,可以进行开放手术、腹腔镜手术和机器人手术。我们报告了一名患有胃腺癌合并SIT的患者,该患者接受了远端胃切除术加胃肠吻合术,同时进行了横结肠切除和吻合以及卡培他滨-奥沙利铂化疗。术后过程顺利。据我们所知,英文文献中仅报道了13例SIT患者发生弥漫型胃癌的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/075a/9754147/45100d8114fc/cureus-0014-00000031538-i01.jpg

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