社区中抗抑郁药的处方是否存在季节性变化？
Is there seasonal variation in the prescribing of antidepressants in the community?
作者信息
Skegg K, Skegg D C, McDonald B W
机构信息
Department of Psychological Medicine, University of Otago, Dunedin, New Zealand.
出版信息
J Epidemiol Community Health. 1986 Dec;40(4):285-8. doi: 10.1136/jech.40.4.285.
The prescribing of antidepressants by general practitioners might be expected to reflect the incidence of depression in the community. In a two-year study of the prescriptions issued by English general practitioners to a population of 40,000 people, the rates of initiating treatment with antidepressants were analysed by month. There was seasonal variation in new antidepressant prescribing for men (p less than 0.025), with peaks in early June and early December, but no significant seasonality for women. The bimodal pattern in men was similar to a recently reported seasonal variation in general practice consultations for depression.
全科医生开具抗抑郁药的情况可能会反映社区中抑郁症的发病率。在一项针对4万名英国人的为期两年的全科医生处方研究中，按月分析了开始使用抗抑郁药治疗的比率。男性新开具抗抑郁药的情况存在季节性变化（p小于0.025），在6月初和12月初出现峰值，但女性没有明显的季节性。男性的双峰模式与最近报道的抑郁症全科诊疗中的季节性变化相似。
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