Department of Otorhinolaryngology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan City, 430022, Hubei Province, People's Republic of China.
Institute of Otorhinolaryngology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, China.
J Neurol. 2023 Apr;270(4):1955-1968. doi: 10.1007/s00415-022-11532-x. Epub 2022 Dec 23.
Meniere's disease (MD) represents one of the vertigo disorders characterized by triad symptoms (recurrent vertigo, fluctuating hearing loss, tinnitus or ear fullness). The diagnosis of MD relies on the accurate and detailed taking of medical history, and the differentiation between MD and vestibular migraine (VM) is of critical importance from the perspective of the treatment efficacy. VM is a highly prevalent vertigo condition and its typical symptoms (headache, vestibular symptoms, cochlear symptoms) mimic those of MD. Furthermore, the misdiagnosis in MD and VM could lead to VM patients mistakenly receiving the traumatic treatment protocol designed for MD, and sustaining unnecessary damage to the inner ear. Fortunately, thanks to the advances in examination technologies, the barriers to their differentiation are being gradually removed. These advances enhance the diagnostic accuracy of vertigo diseases, especially VM and MD. This review focused on the differentiation of VM and MD, with an attempt to synthesize existing data on the relevant battery of differentiation diagnosis (covering core symptoms, auxiliary tests [audiometry, vestibular tests, endolymphatic hydrops tests]) and longitudinal follow-up. Since the two illnesses are overlapped in all aspects, no single test is sufficiently specific on its own, however, patterns containing all or at least some features boost specificity.
梅尼埃病(MD)是一种眩晕障碍,其特征为三联征症状(反复发作性眩晕、波动性听力损失、耳鸣或耳闷胀感)。MD 的诊断依赖于对病史的准确和详细采集,而从治疗效果的角度来看,MD 和前庭性偏头痛(VM)的区分至关重要。VM 是一种高发的眩晕疾病,其典型症状(头痛、前庭症状、耳蜗症状)与 MD 相似。此外,MD 和 VM 的误诊可能导致 VM 患者错误地接受专为 MD 设计的创伤性治疗方案,从而对内耳造成不必要的损害。幸运的是,由于检查技术的进步,区分它们的障碍正在逐渐消除。这些进展提高了眩晕疾病的诊断准确性,尤其是 VM 和 MD。本综述重点讨论了 VM 和 MD 的区分,试图综合相关鉴别诊断的现有数据(涵盖核心症状、辅助检查[听力、前庭检查、内淋巴积水检查])和纵向随访。由于这两种疾病在各个方面都有重叠,因此没有单一的检查具有足够的特异性,但包含所有或至少部分特征的模式可提高特异性。