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新冠疫情封锁期间严重肠病性肢端皮炎的罕见病例

A Rare Case Of Severe Acrodermatitis Enteropathica During Covid-19 Lockdown.

机构信息

Bolan Medical Complex Hospital Quetta.

Khyber teaching Hospital Peshawar.

出版信息

J Ayub Med Coll Abbottabad. 2022 Oct-Dec;34(4):880-882. doi: 10.55519/JAMC-04-10371.

Abstract

Acrodermatitis Enteropathica is a rare hereditary condition characterized by perioral dermatitis, diarrhoea, and alopecia. Aetiology includes autosomal recessive inheritance and acquired causes such as protein malnutrition, malabsorption syndromes, premature births, parenteral nutrition, chronic illnesses, and alcoholism. We report a rare case of a 12-year-old boy who presented with cutaneous manifestations involving the whole body, diarrhoea, and sparse hairs. A low level of plasma zinc, and alkaline phosphatase level was found, and he was started on zinc supplements. He significantly improved in a few days, and was discharged after counselling the parents about treatment compliance. This case highlights importance of early diagnosis, and the importance of treatment compliance in Acrodermatitis Enteropathica. It also stresses the need to take measures to ensure the provision of health facilities especially in remote areas.

摘要

肠病性肢端皮炎是一种罕见的遗传性疾病,其特征为口周性皮炎、腹泻和脱发。病因包括常染色体隐性遗传和获得性因素,如蛋白质营养不良、吸收不良综合征、早产、肠外营养、慢性疾病和酗酒。我们报告了一例罕见的 12 岁男孩病例,他表现为全身皮肤表现、腹泻和稀疏的毛发。发现血浆锌和碱性磷酸酶水平低,开始补锌治疗。几天后他明显好转,在向父母告知治疗依从性后出院。本病例强调了早期诊断的重要性,以及肠病性肢端皮炎治疗依从性的重要性。它还强调需要采取措施确保提供卫生设施,特别是在偏远地区。

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