[Arrhythmogenic effect of anti-arrhythmia agents in patients with paroxysmal supraventricular reciprocal tachycardia].

A retrospective study of the results of consecutive testing of antiarrhythmic agents was carried out in 82 patients with paroxysmal reciprocal supraventricular tachycardia. Arrhythmogenic effects of anti-arrhythmic drugs were detected in 22 (6.1%) of 359 pharmacologic tests. The electrophysiologic basis of arrhythmogenic effect is delayed impulse conduction at some point of the blood flow pathway, conducive to the emergence or maintenance of the re-entry phenomenon.