Stark Cain W, Isaamullah Mir, Hassan Shareef S, Dyara Omar, Abd-Elsayed Alaa
Department of Anesthesiology, Medical College of Wisconsin, Wauwatosa, WI, USA.
Chantilly High School, Chantilly, VA, USA.
Pain Ther. 2023 Apr;12(2):341-354. doi: 10.1007/s40122-022-00470-1. Epub 2022 Dec 29.
Chronic pain is a debilitating condition with a growing prevalence both in the USA and globally. The complex nature of this condition necessitates a multimodal approach to pain management that extends beyond the established pharmaceutical interventions currently employed. A variety of devices comprising both invasive and noninvasive approaches are available to patients, serving as adjuvants to existing regimens. The benefits of these interventions are notable for their lack of addiction potential, potential for patient autonomy regarding self-administration, minimal to no drug interaction, and overall relative safety. However, there remains a need for further research and more robust clinical trials to assess the true efficacy of these interventions and elucidate if there is an underlying physiological mechanism to their benefit in treating chronic pain or if their effect is predominantly placebo in nature. Regardless, the field of device-based intervention and treatment remains an evolving field with much promise for the future chronic pain management.
慢性疼痛是一种使人衰弱的病症,在美国和全球范围内的患病率都在不断上升。这种病症的复杂性需要一种多模式的疼痛管理方法,该方法要超越目前所采用的既定药物干预措施。患者可以使用包括侵入性和非侵入性方法在内的多种设备,作为现有治疗方案的辅助手段。这些干预措施的好处显著,包括没有成瘾潜力、患者在自我给药方面具有自主性、药物相互作用最小或没有、以及总体相对安全性高。然而,仍需要进一步研究和更有力的临床试验,以评估这些干预措施的真正疗效,并阐明它们在治疗慢性疼痛方面有益的潜在生理机制,或者其效果是否主要是安慰剂性质的。无论如何,基于设备的干预和治疗领域仍是一个不断发展的领域,对未来的慢性疼痛管理有着很大的前景。