GHU APHP. Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, France.
Sorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.
Int J Public Health. 2022 Dec 15;67:1604792. doi: 10.3389/ijph.2022.1604792. eCollection 2022.
The aim of this study was to estimate the prevalence of anti-microbial resistance (AMR) carriage and its risk factors in hospitalized migrants. Additionally, the prevalence of infectious diseases was evaluated, as well as symptoms of psychological trauma. We conducted a retrospective monocentric cross-sectional study including all migrant patients recently arrived and hospitalised over a one-year period. Among 101 patients, seventy-nine percent originated from Sub-Saharan Africa. The overall AMR carriage rate was 20.7% [95% CI: 12.4; 28.9%]. We isolated 5/92 methicillin-resistant strains (5.4%) and 15/92 extended-spectrum beta-lactamase-producing Enterobacteriaceae (16.4%). AMR carriage was associated with older age, region of origin and length of migration. Rates of HIV, HBV, and HCV infection were 39.6%, 32.7%, and 5%, reflecting sampling bias linked to reasons for hospitalization. Eleven percent had serological evidence of treponemasis and 7.8% had infection. Symptoms of depression or post-traumatic stress disorder were observed for more than half the patients. It appears essential to offer a systematic and comprehensive post-arrival screening of AMR carriage, infectious diseases and psychological trauma to subjects who experienced migration.
本研究旨在评估住院移民中抗微生物药物耐药(AMR)携带率及其危险因素。此外,还评估了传染病的流行情况以及心理创伤的症状。我们进行了一项回顾性单中心横断面研究,纳入了过去一年中最近到达并住院的所有移民患者。在 101 名患者中,79%来自撒哈拉以南非洲。总体 AMR 携带率为 20.7%[95%CI:12.4%;28.9%]。我们分离出 5/92 株耐甲氧西林金黄色葡萄球菌(5.4%)和 15/92 株产超广谱β-内酰胺酶的肠杆菌科(16.4%)。AMR 携带与年龄较大、原籍地区和移民时间长短有关。HIV、HBV 和 HCV 感染率分别为 39.6%、32.7%和 5%,这反映了因住院而导致的采样偏倚。11%的患者有梅毒血清学证据,7.8%的患者有 感染。超过一半的患者出现抑郁或创伤后应激障碍症状。对于经历过移民的人群,提供针对 AMR 携带、传染病和心理创伤的系统和全面的到达后筛查似乎至关重要。