基层医疗人员在监督呼吸道合胞病毒感染婴儿治疗过程中接触利巴韦林气雾剂的环境暴露情况。
Environmental exposure of primary care personnel to ribavirin aerosol when supervising treatment of infants with respiratory syncytial virus infections.
作者信息
Rodriguez W J, Bui R H, Connor J D, Kim H W, Brandt C D, Parrott R H, Burch B, Mace J
机构信息
Children's Hospital National Medical Center, George Washington University School of Medicine and the Health Sciences, Washington, D.C. 20010.
出版信息
Antimicrob Agents Chemother. 1987 Jul;31(7):1143-6. doi: 10.1128/AAC.31.7.1143.
The potential exposure to ribavirin aerosol in the environment was assessed in nurses caring for infants and children with severe lower respiratory tract infections due to respiratory syncytial virus. Ribavirin aerosol was administered via a ventilator, oxygen tent, or oxygen hood. Participants worked directly with infants receiving ribavirin for 20.0 to 35.0 h over a 3-day period. No toxic or adverse effects of ribavirin aerosol were observed in any of the 19 nurses studied, and ribavirin was not detected in erythrocytes, plasma, or urine collected after the potential exposure period.
对护理因呼吸道合胞病毒引起的严重下呼吸道感染的婴幼儿的护士，评估其在环境中接触利巴韦林气雾剂的可能性。利巴韦林气雾剂通过呼吸机、氧气帐或氧气头罩给药。参与者在3天时间内直接接触接受利巴韦林治疗的婴儿20.0至35.0小时。在所研究的19名护士中，未观察到利巴韦林气雾剂的任何毒性或不良反应，且在潜在接触期后采集的红细胞、血浆或尿液中未检测到利巴韦林。
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