Gupta Vikas, Sidam Shaila, Behera Ganakalyan, Kumar Aman, Mishra Utkal P
Otorhinolaryngology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Otolaryngology - Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Cureus. 2022 Dec 10;14(12):e32382. doi: 10.7759/cureus.32382. eCollection 2022 Dec.
Introduction Cervical necrotizing fasciitis is an acute, progressive, and rapidly spreading soft tissue infection affecting the fascial planes of the head and neck region. It has high morbidity and mortality rate. In this study, we have reviewed cervical necrotizing fasciitis cases treated in our department and analyzed the various risk factors, laboratory indices, and treatment modalities that affect the prognosis of this deadly disease. Design and method This is a retrospective review. We have reviewed the medical records and charts of seven patients hospitalized in our institute with the diagnosis of cervical necrotizing fasciitis between 2015 and 2019. Results Of the seven patients, six were male and one was female. The mean age was 49.8 years (range: 38-70 years). Etiology was found to be odontogenic infection in five (71%) cases. The presenting feature in all cases was tender cervical swelling. Intraoperatively, the submandibular triangle was found to be involved in all cases (100%) followed by the carotid triangle in five (71%) cases and the submental triangle in three (42%) cases. The most common comorbidities associated with cervical necrotizing fasciitis were found to be uncontrolled diabetes mellitus and anemia. All patients underwent emergency aggressive surgical debridement and culture-directed broad-spectrum antibiotics (100%). Additional procedures in the form of tracheostomy were required in two (28%) cases and skin grafting in two (28%) cases. One patient in our series developed sepsis with descending mediastinitis. The average hospital stay was 27 days. All the patients survived with no mortality. Conclusion Cervical necrotizing fasciitis should be diagnosed early. Early initiation of broad-spectrum antibiotics and aggressive surgical debridement are the two key management strategies that can improve survival. Strict glycemic control and correction of anemia result in a favorable outcome.
引言
颈部坏死性筋膜炎是一种急性、进行性且迅速蔓延的软组织感染,累及头颈部区域的筋膜平面。其发病率和死亡率都很高。在本研究中,我们回顾了在我科治疗的颈部坏死性筋膜炎病例,并分析了影响这种致命疾病预后的各种风险因素、实验室指标和治疗方式。
设计与方法
这是一项回顾性研究。我们查阅了2015年至2019年期间在我院住院诊断为颈部坏死性筋膜炎的7例患者的病历和图表。
结果
7例患者中,6例为男性,1例为女性。平均年龄为49.8岁(范围:38 - 70岁)。病因发现5例(71%)为牙源性感染。所有病例的主要表现为颈部压痛性肿胀。术中发现所有病例(100%)均累及下颌下三角,其次是5例(71%)累及颈动脉三角,3例(42%)累及颏下三角。发现与颈部坏死性筋膜炎相关的最常见合并症是未控制的糖尿病和贫血。所有患者均接受了紧急积极的手术清创和经验性广谱抗生素治疗(100%)。2例(28%)患者需要进行气管切开术,2例(28%)患者需要进行植皮手术。我们系列中的1例患者发生了败血症并伴有下行性纵隔炎。平均住院时间为27天。所有患者均存活,无死亡病例。
结论
颈部坏死性筋膜炎应早期诊断。早期使用广谱抗生素和积极的手术清创是改善生存的两个关键管理策略。严格控制血糖和纠正贫血可带来良好的预后。