Bucknall C A, Lewis S, Vincent R, Jackson G, Jewitt D E, Chamberlain D A
Department of Cardiology, Royal Sussex County Hospital, Brighton.
Br Heart J. 1987 Sep;58(3):245-50. doi: 10.1136/hrt.58.3.245.
The efficacy of transvenous cardioversion and defibrillation for treating life threatening spontaneous ventricular arrhythmias was assessed in a study of 17 patients in a cardiac care unit. Eleven had ventricular tachycardia, five had ventricular fibrillation, and one had both. Transvenous cardioversion successfully terminated tachyarrhythmias on 42 separate occasions in ten patients. Stable electrode positions could not be achieved in two patients, recurrent late displacement occurred in one, and four patients had no further arrhythmias requiring cardioversion once the lead was placed. The energy levels required for successful cardioversion ranged from 0.05 J to 25 J for ventricular tachycardia and from 1 J to 25 J for ventricular fibrillation. The nine successful shocks of 1 J or less did not require sedation or general anaesthesia. High energy (25 J) endocardial shocks were unsuccessful in terminating arrhythmias in two patients, one with ventricular tachycardia and the other with both ventricular tachycardia and fibrillation. Minor unwanted effects of endocardial shocks occurred in five patients. These were acceleration of ventricular tachycardia in two patients and complications of pacing via the special lead in three others: failure of sensing occurred in all three and one patient also had a transient rise in pacing threshold. A postmortem examination in one patient who had received three unsuccessful high energy shocks revealed localised endocardial necrosis at the site of the distal electrode. Transvenous cardioversion offers advantages over external cardioversion but at present practical difficulties limit its application to patients with recurrent ventricular arrhythmias that cannot readily be controlled by conventional methods.
在心脏监护病房对17例患者进行的一项研究中,评估了经静脉心脏复律和除颤治疗危及生命的自发性室性心律失常的疗效。11例患者患有室性心动过速,5例患有心室颤动,1例两者皆有。经静脉心脏复律在10例患者的42次不同情况下成功终止了快速心律失常。2例患者无法获得稳定的电极位置,1例出现反复晚期移位,4例患者在放置电极后未再出现需要心脏复律的心律失常。成功心脏复律所需的能量水平,室性心动过速为0.05 J至25 J,心室颤动为1 J至25 J。9次1 J或更低能量的成功电击无需镇静或全身麻醉。25 J的高能量心内膜电击在2例患者中未能成功终止心律失常,1例为室性心动过速,另1例为室性心动过速合并心室颤动。5例患者出现心内膜电击的轻微不良影响。其中2例患者出现室性心动过速加速,另外3例患者出现通过特殊电极起搏的并发症:3例均出现感知失败,1例患者的起搏阈值也出现短暂升高。1例接受3次高能量电击未成功的患者尸检显示,远端电极部位存在局限性心内膜坏死。经静脉心脏复律比体外心脏复律具有优势,但目前实际困难限制了其应用于常规方法难以控制的复发性室性心律失常患者。