Imtiaz Sameer, Nigatu Yeshambel T, Ali Farihah, Douglas Laura, Hamilton Hayley A, Rehm Jürgen, Rueda Sergio, Schwartz Robert M, Wells Samantha, Elton-Marshall Tara
Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario M5S 2S1, Canada.
Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario M5S 2S1, Canada; Dalla Lana School of Public Health, University of Toronto, 6th Floor, 155 College Street, Toronto, Ontario M5T 3M7, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada.
Drug Alcohol Depend. 2023 Mar 1;244:109765. doi: 10.1016/j.drugalcdep.2023.109765. Epub 2023 Jan 6.
In the context of cannabis legalization in Canada, we examined the effects on cannabis patterns of consumption, including cannabis use, daily cannabis use and cannabis-related problems. In addition, we examined differential effects of cannabis legalization by age and sex.
A pre-post design was operationalized by combining 19 iterations of the Centre for Addiction and Mental Health (CAMH) Monitor Surveys (N = 52,260; 2001-2019): repeated, population-based, cross-sectional surveys of adults in Ontario. Participants provided self-reports of cannabis use (past 12 months), daily cannabis use (past 12 months) and cannabis-related problems though telephone interviews. The effects of cannabis legalization on cannabis patterns of consumption were examined using logistic regression analyses, with testing of two-way interactions to determine differential effects by age and sex.
Cannabis use prevalence increased from 11 % to 26 % (p < 0.0001), daily cannabis use prevalence increased from 1 % to 6 % (p < 0.0001) and cannabis-related problems prevalence increased from 6 % to 14 % (p < 0.0001) between 2001 and 2019. Cannabis legalization was associated with an increased likelihood of cannabis use (OR, 95 % CI: 1.62, 1.40-1.86), daily cannabis use (1.59, 1.21-2.07) and cannabis-related problems (1.53, 1.20-1.95). For cannabis-related problems, a significant two-way interaction was observed between cannabis legalization and age (p = 0.0001), suggesting differential effects among adults ≥55 years.
Cannabis legalization was associated with an increased likelihood of cannabis use, daily cannabis use and cannabis-related problems. Given increases in these cannabis patterns of consumption, broader dissemination and uptake of targeted prevention tools is indicated.
在加拿大大麻合法化的背景下,我们研究了其对大麻消费模式的影响,包括大麻使用、每日大麻使用及与大麻相关的问题。此外,我们还研究了大麻合法化在年龄和性别方面的差异影响。
采用前后对照设计,将成瘾与心理健康中心(CAMH)监测调查的19次迭代(N = 52260;2001 - 2019年)相结合:这是对安大略省成年人进行的基于人群的重复横断面调查。参与者通过电话访谈提供了关于大麻使用(过去12个月)、每日大麻使用(过去12个月)及与大麻相关问题的自我报告。使用逻辑回归分析研究大麻合法化对大麻消费模式的影响,并通过检验双向交互作用来确定年龄和性别的差异影响。
2001年至2019年间,大麻使用流行率从11%增至26%(p < 0.0001),每日大麻使用流行率从1%增至6%(p < 0.0001),与大麻相关问题的流行率从6%增至14%(p < 0.0001)。大麻合法化与大麻使用可能性增加(比值比,95%置信区间:1.62,1.40 - 1.86)、每日大麻使用(1.59,1.21 - 2.07)及与大麻相关问题(1.53,1.20 - 1.95)相关。对于与大麻相关的问题,在大麻合法化与年龄之间观察到显著的双向交互作用(p = 0.0001),表明在≥55岁的成年人中存在差异影响。
大麻合法化与大麻使用、每日大麻使用及与大麻相关问题的可能性增加相关。鉴于这些大麻消费模式的增加,表明有必要更广泛地传播和采用针对性的预防工具。