心室性心动过速放射外科治疗（RAVENTA）试验中的质量保证流程，用于心脏射频消融术中电解剖标测与放射治疗计划成像数据的融合。
Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation.
作者信息
Mayinger Michael, Boda-Heggemann Judit, Mehrhof Felix, Krug David, Hohmann Stephan, Xie Jingyang, Ehrbar Stefanie, Kovacs Boldizsar, Merten Roland, Grehn Melanie, Zaman Adrian, Fleckenstein Jens, Kaestner Lena, Buergy Daniel, Rudic Boris, Kluge Anne, Boldt Leif-Hendrik, Dunst Jürgen, Bonnemeier Hendrik, Saguner Ardan M, Andratschke Nicolaus, Blanck Oliver, Schweikard Achim
机构信息
Department of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Department of Radiation Oncology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
出版信息
Phys Imaging Radiat Oncol. 2022 Dec 26;25:100406. doi: 10.1016/j.phro.2022.12.003. eCollection 2023 Jan.
A novel quality assurance process for electroanatomical mapping (EAM)-to-radiotherapy planning imaging (RTPI) target transport was assessed within the multi-center multi-platform framework of the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial. A stand-alone software (CARDIO-RT) was developed to enable platform independent registration of EAM and RTPI of the left ventricle (LV), based on pre-generated radiotherapy contours (RTC). LV-RTC were automatically segmented into the American-Heart-Association 17-segment-model and a manual 3D-3D method based on EAM 3D-geometry data and a semi-automated 2D-3D method based on EAM screenshot projections were developed. The quality of substrate transfer was evaluated in five clinical cases and the structural analyses showed substantial differences between manual target transfer and target transport using CARDIO-RT.
在心室性心动过速放射外科治疗（RAVENTA）试验的多中心多平台框架内，评估了一种用于从电解剖标测（EAM）到放射治疗计划成像（RTPI）的靶点传输的新型质量保证流程。开发了一个独立软件（CARDIO-RT），以基于预先生成的放射治疗轮廓（RTC）实现左心室（LV）的EAM和RTPI的平台独立配准。LV-RTC被自动分割为美国心脏协会的17段模型，并开发了基于EAM 3D几何数据的手动3D-3D方法和基于EAM屏幕截图投影的半自动2D-3D方法。在五个临床病例中评估了底物传输的质量，结构分析显示手动靶点传输与使用CARDIO-RT进行靶点传输之间存在显著差异。
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