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作为可穿戴设备的柔软生物相容性材料和类皮肤电子器件:对约翰·A·罗杰斯的采访

Soft, biocompatible materials and skin-like electronics as wearable devices: an interview with John A. Rogers.

作者信息

Song By Enming

机构信息

Enming Song is a Professor at the Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Fudan University.

出版信息

Natl Sci Rev. 2022 Sep 17;10(1):nwac191. doi: 10.1093/nsr/nwac191. eCollection 2023 Jan.

Abstract

Recent advances in active materials, micro-fabrication techniques, ultra-miniaturized design approaches and hybrid device layouts form the foundations for emerging classes of unusual systems that can capture physiological signals from the human body in a physically imperceptible fashion at nearly any anatomical location, external on the skin or internal on vital organ systems. Of particular interest with these technologies are their thin geometries, flexible/stretchable physical properties and unique form factors, to enable conformal and gentle contacts with soft, curved and dynamic surfaces of living tissues. Commercial embodiments of skin-integrated devices with clinical-grade monitoring capabilities are just now becoming widely available not only in developed countries but also in the most resource-constrained areas of the globe. A specific example is in skin-like-sometimes referred to as 'epidermal'-wireless electronics for continuous monitoring of essential markers of physiological health status, with accuracy and reliability comparable to that of expensive, wired-based systems currently used with patients in intensive care units, but cost-effectively and applicable in any setting-in hospitals, health clinics, work environments or in the home. These technologies have the potential to revolutionize diagnostic and therapeutic approaches for the care of patients. spoke to one of the scientific leaders in this field-a 2009 MacArthur Fellow, the winner of the 2022 US National Academy of Sciences James Prize in Science and Technology Integration and one of the few individuals in history to be elected to all three US National Academies, namely the National Academy of Engineering, the National Academy of Science and the National Academy of Medicine, Professor John A. Rogers, the Director of the Querrey-Simpson Institute of Bioelectronics at Northwestern University on the recent advancements and the prospects of soft, biocompatible electronic systems and skin-like wearable devices.

摘要

活性材料、微制造技术、超小型化设计方法和混合设备布局的最新进展,为新型特殊系统奠定了基础。这些系统能够以几乎不可察觉的方式,在人体几乎任何解剖位置(皮肤外部或重要器官系统内部)捕捉生理信号。这些技术特别引人关注的是其薄型几何结构、灵活/可拉伸的物理特性以及独特的外形因素,从而能够与活组织的柔软、弯曲和动态表面实现贴合且温和的接触。具有临床级监测能力的皮肤集成设备的商业产品,不仅在发达国家,而且在全球资源最有限的地区,都刚刚开始广泛普及。一个具体例子是类似皮肤的——有时被称为“表皮”的——无线电子设备,用于持续监测生理健康状况的重要指标,其准确性和可靠性与目前重症监护病房中患者使用的昂贵有线系统相当,但具有成本效益,适用于任何环境——医院、健康诊所、工作场所或家庭。这些技术有可能彻底改变患者护理的诊断和治疗方法。我采访了该领域的一位科学领军人物——2009年麦克阿瑟奖获得者、2022年美国国家科学院詹姆斯科技融合奖得主,也是历史上为数不多同时入选美国国家工程院、美国国家科学院和美国国家医学院这三个美国国家科学院的人之一,西北大学奎里 - 辛普森生物电子研究所所长约翰·A·罗杰斯教授,探讨了软质、生物相容性电子系统和类皮肤可穿戴设备的最新进展和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c4d/9843121/5338b3bf6d7b/nwac191fig1.jpg

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