Arunachalam Karuppusamy, Sasidharan Sreeja Puthanpura, Yang Xuefei
Key Laboratory of Economic Plants and Biotechnology, The Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Food Chem Adv. 2022 Oct;1:100023. doi: 10.1016/j.focha.2022.100023. Epub 2022 Mar 2.
The World Health Organization (WHO) declared COVID-19 as a pandemic on March 11, 2020, because of its widespread transmission and infection rates. The unique severe disease was found in Wuhan, China, since December 2019, and swiftly spread throughout the world. Natural chemicals derived from herbal medicines and medicinal mushrooms provide a significant resource for the development of novel antiviral drugs. Many natural drugs have been proven to have antiviral properties against a variety of virus strains, such as the coronavirus and the herpes simplex virus (HSV).. In this research, successful dietary treatments for different COVID illnesses were compared to potential of mushroom products in its therapy. In Google Scholar, Science Direct, PubMed, and Scopus, search keywords like COVID, COVID-19, SARS, MERS, mushrooms, and their compounds were utilized. In this review of the literature we foucsed popular mushrooms such as Peck Murill, (Berk.) Sacc. (Curtis.) P. Karst. (Dicks.) Gray (Bull.) Pers. (Arch. Ex Pers.) Pilát. (Berk.) Pegler (Jacq.) P. Kumm. F.A. Wolf, and (L.) Lloyd.,. Changed forms of β-Glucan seem to have a good impact on viral replication suppression and might be used in future studies. However, the results seems terpenoids, lectins, glycoproteins, lentinan, galactomannan, and polysaccharides from mushrooms are promising prophylactic or therapeutic agents against COVID-19.
2020年3月11日，世界卫生组织（WHO）宣布新型冠状病毒肺炎（COVID-19）为大流行病，因其传播广泛且感染率高。自2019年12月以来，这种独特的严重疾病在中国武汉被发现，并迅速蔓延至全球。源自草药和药用蘑菇的天然化学物质为新型抗病毒药物的开发提供了重要资源。许多天然药物已被证明对多种病毒株具有抗病毒特性，如冠状病毒和单纯疱疹病毒（HSV）。在本研究中，将针对不同COVID疾病的成功饮食疗法与蘑菇产品在其治疗中的潜力进行了比较。在谷歌学术、科学Direct、PubMed和Scopus中，使用了如COVID、COVID-19、SARS、MERS、蘑菇及其化合物等搜索关键词。在本次文献综述中，我们聚焦于如佩克穆里尔蘑菇、（伯克）萨卡蘑菇、（柯蒂斯）P. 卡斯特蘑菇、（迪克斯）格雷蘑菇、（布尔）佩尔斯蘑菇、（阿奇·埃克斯·佩尔斯）皮拉特蘑菇、（伯克）佩格勒蘑菇、（雅克）P. 库姆蘑菇、F.A. 沃尔夫蘑菇以及（L.）劳埃德蘑菇等常见蘑菇。β-葡聚糖的不同形式似乎对病毒复制抑制有良好影响，可能会在未来研究中得到应用。然而，结果表明蘑菇中的萜类化合物、凝集素、糖蛋白、香菇多糖、半乳甘露聚糖和多糖是对抗COVID-19有前景的预防或治疗剂。
