Frangos Jason E, Amini Andrew E, Schmidt Birgitta, Ganske Ingrid M
Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Pediatr Dermatol. 2023 Sep-Oct;40(5):877-878. doi: 10.1111/pde.15242. Epub 2023 Jan 24.
We report a case of melanosis of the areola in a 7-year-old girl with early thelarche. Areolar melanosis is a rare condition previously only described in women over 25 years of age, often in the setting of pregnancy. This case supports a theory that hyperpigmentation may be associated with increased sensitivity to hormonal stimulation in areas with greater populations of melanocytes.
我们报告一例7岁性早熟女童乳晕黑变病的病例。乳晕黑变病是一种罕见病症,此前仅在25岁以上女性中有所描述,且多见于孕期。该病例支持一种理论,即色素沉着过度可能与黑素细胞数量较多区域对激素刺激的敏感性增加有关。