Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Internal Medicine, An-Najah National University Hospital, Nablus, Palestine.
BMC Nephrol. 2023 Jan 26;24(1):21. doi: 10.1186/s12882-023-03064-x.
Kidney failure is rapidly rising in Palestine, as the number of patients receiving maintenance dialysis has quadrupled in the last 15 years. In this study, we share an overview of our experience growing a peritoneal dialysis (PD) program from zero to 178 patients in 5 years at An-Najah National University Hospital in Palestine, presenting some challenges and ways to overcome them.
This was a single-center retrospective study of patients treated with PD from November 2016 to December 2021. Demographic and clinical data were obtained for each patient. In addition, PD discontinuation, peritonitis, and mortality rates were calculated and presented as the primary patient outcomes.
A total of 158 patients were eligible for the study. The mean age was 51.8 ± 16.4 years, and 53.8% of patients were male. Diabetic nephropathy was the most common cause of kidney failure. 63 episodes of peritonitis were diagnosed in 48 patients (30.4%) for a rate of 1 episode/ 38.2 patient-months (0.31 episodes/ patient-years). 20 patients had their PD treatment discontinued, mainly due to psychosocial reasons and infectious and mechanical complications. Death was the fate of 27 patients, with cardiovascular disease and COVID-19 being the two main causes.
The outcomes of this experience proved favorable and showed that PD could serve as a viable option for kidney failure patients in Palestine. Moreover, this study can serve as an example for other places where circumstances are challenging to take the initiative of starting their PD programs.
在巴勒斯坦,肾衰竭的发病率迅速上升,在过去的 15 年中,接受维持性透析治疗的患者人数增加了三倍。在这项研究中,我们分享了在巴勒斯坦纳贾赫国立大学医院在 5 年内从零开始将腹膜透析(PD)项目扩展到 178 名患者的经验概述,介绍了一些挑战和克服这些挑战的方法。
这是一项针对 2016 年 11 月至 2021 年 12 月期间接受 PD 治疗的患者的单中心回顾性研究。为每位患者获取人口统计学和临床数据。此外,还计算了 PD 终止、腹膜炎和死亡率,并将其作为主要患者结局进行呈现。
共有 158 名患者符合研究条件。平均年龄为 51.8±16.4 岁,53.8%的患者为男性。糖尿病肾病是肾衰竭的最常见原因。48 名患者中诊断出 63 例腹膜炎(30.4%),腹膜炎发生率为 1 例/38.2 患者-月(0.31 例/患者-年)。20 名患者停止了 PD 治疗,主要是由于心理社会原因以及感染和机械并发症。27 名患者死亡,心血管疾病和 COVID-19 是两个主要原因。
这项经验的结果证明是有利的,表明 PD 可以作为巴勒斯坦肾衰竭患者的可行选择。此外,本研究可以为其他环境条件具有挑战性的地方提供一个范例,以主动开展 PD 项目。