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1例上颌骨尤因肉瘤采用新提出的多模式方法治疗以获得最佳疗效的罕见病例

A Rare Case of Ewing's Sarcoma of Maxilla Managed with a Newly Proposed Multimodality Approach to Achieve Optimal Outcome.

作者信息

Raghani Manish J, Bajaj Chakshu, Ansari Hafiz Md Nasimuddin

机构信息

Present Address: Oral and Maxillofacial Surgery Unit, All India Institute of Medical Sciences, Raipur, India.

Department of Dentistry, Oral and Maxillofacial Surgery Unit, All India Institute of Medical Sciences, Raipur, India.

出版信息

J Maxillofac Oral Surg. 2023 Mar;22(1):258-261. doi: 10.1007/s12663-022-01762-x. Epub 2022 Jul 23.

Abstract

Rare case of Ewing's Sarcoma of maxilla managed with newly proposed multimodalityapproach in which First neo-adjuvant chemotherapy was done to shrink the size oftumor mass and control possible occult distant metastasis and in the second phase surgical management that is followed by adjuvant chemotherapy was done. During Surgical phase, instead of doing a complete surgical resection, we have decided intraoperatively and performed only curettage of the tumor mass left after shrinkage of the tumor mass post chemotherapy phase. This concludes that there is the scope of trying newer ideas for management and, thus, more contemporary approaches for this rare entity. Like in our case, curettage of the tumor rather than radical resection as a part of multimodality approach also gave optimal outcome.

摘要

上颌骨尤文肉瘤罕见病例采用新提出的多模式方法进行治疗,首先进行新辅助化疗以缩小肿瘤肿块大小并控制可能隐匿的远处转移,第二阶段进行手术治疗,随后进行辅助化疗。在手术阶段,我们术中决定不进行完整的手术切除,而是仅对化疗后肿瘤肿块缩小后残留的肿瘤进行刮除术。这表明对于该罕见疾病的治疗有尝试新想法的空间,因此也有更多当代治疗方法。就像我们的病例一样,作为多模式方法一部分的肿瘤刮除术而非根治性切除术也取得了最佳效果。

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