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利用纳米脂质体包封维生素:最新进展与展望

Encapsulation of Vitamins Using Nanoliposome: Recent Advances and Perspectives.

作者信息

Aman Mohammadi Masoud, Farshi Parastou, Ahmadi Parisa, Ahmadi Azam, Yousefi Mohammad, Ghorbani Marjan, Hosseini Seyede Marzieh

机构信息

Student Research Committee, Department of Food Technology, Faculty of Nutrition Science and Food Technology, Nutritional and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Food Science Institute, Kansas State University, Manhattan KS, USA.

出版信息

Adv Pharm Bull. 2023 Jan;13(1):48-68. doi: 10.34172/apb.2023.005. Epub 2021 Oct 10.

Abstract

Nowadays the importance of vitamins is clear for everyone. However, many patients are suffering from insufficient intake of vitamins. Incomplete intake of different vitamins from food sources due to their destruction during food processing or decrease in their bioavailability when mixing with other food materials, are factors resulting in vitamin deficiency in the body. Therefore, various lipid based nanocarriers such as nanoliposomes were developed to increase the bioavailability of bioactive compounds. Since the function of nanoliposomes containing vitamins on the body has a direct relationship with the quality of produced nanoliposomes, this review study was planned to investigate the several aspects of liposomal characteristics such as size, polydispersity index, zeta potential, and encapsulation efficiency on the quality of synthesized vitamin-loaded nanoliposomes.

摘要

如今,维生素的重要性已为众人所知。然而,许多患者存在维生素摄入不足的问题。由于在食品加工过程中维生素被破坏,或者与其他食物原料混合时其生物利用度降低,导致从食物来源中不同维生素的摄入不完整,这些都是导致体内维生素缺乏的因素。因此,人们开发了各种基于脂质的纳米载体,如纳米脂质体,以提高生物活性化合物的生物利用度。由于含维生素的纳米脂质体对身体的作用与所制备纳米脂质体的质量直接相关,本综述研究旨在探讨脂质体特性的几个方面,如大小、多分散指数、zeta电位和包封效率对合成的载维生素纳米脂质体质量的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b011/9871282/1e94f75d2bf5/apb-13-48-g001.jpg

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