Department of Orthopaedics, Western Hospital Group, Alingsås, Sweden.
Faculty of Medicine, Lund University, Lund, Sweden.
J Bone Joint Surg Am. 2023 Mar 1;105(5):389-396. doi: 10.2106/JBJS.22.01035. Epub 2022 Dec 21.
Although most nondisplaced or minimally displaced femoral neck fractures are routinely treated with internal fixation, high rates of secondary surgical procedures are common, especially in the elderly population. Primary arthroplasty in elderly patients has been proposed as an alternative treatment to reduce the need for a secondary surgical procedure. The objective of this study was to describe the rate of conversion to arthroplasty within 5 years after internal fixation of nondisplaced femoral neck fractures in patients ≥60 years of age.
In this observational cohort study of prospectively collected data from the Swedish Fracture Register (SFR) between 2012 and 2018, cross-matched with the Swedish Arthroplasty Register (SAR), 5,428 nondisplaced femoral neck fractures in patients ≥60 years of age were included. Competing risk analysis was used to estimate conversion rates to arthroplasty and mortality in various age groups at 1, 2, and 5 years.
The cumulative incidence function (CIF) for conversion to arthroplasty was 6.3% at 1 year, 8.1% at 2 years, and 10.1% at 5 years. The conversion rates within 2 years were 6.5% in 60 to 69-year-olds, 9.6% in 70 to 79-year-olds, and 7.8% in ≥80-year-olds. Women had a higher risk of conversion; the hazard ratio (HR) was 1.49 (95% confidence interval [CI], 1.19 to 1.87). The cumulative mortality was 21.3% (95% CI, 20.3% to 22.5%) at 1 year, 31.3% (95% CI, 30.0% to 32.6%) at 2 years, and 54.9% (95% CI, 53.1% to 56.7%) at 5 years. Mortality was higher in men at all time points, and the adjusted 1-year HR was 1.79 (95% CI, 1.61 to 2.00).
One in 10 patients ≥60 years of age treated with internal fixation for a nondisplaced femoral neck fracture underwent conversion to arthroplasty within 5 years, and more than one-half of the conversions occurred within the first year. The risk of conversion was highest in women and in patients 70 to 79 years of age. These data warrant further studies in this frail patient group to identify subgroups of patients who would benefit from primary arthroplasty for nondisplaced femoral neck fractures.
Prognostic Level III . See Instructions for Authors for a complete description of levels of evidence.
尽管大多数无移位或轻度移位的股骨颈骨折通常采用内固定治疗,但二次手术的发生率很高,尤其是在老年人群中。老年人原发性关节置换术已被提议作为减少二次手术需求的替代治疗方法。本研究的目的是描述≥60 岁患者股骨颈无移位骨折内固定后 5 年内关节置换的转化率。
本研究为前瞻性收集 2012 年至 2018 年瑞典骨折登记处(SFR)数据的观察性队列研究,并与瑞典关节置换登记处(SAR)交叉匹配,纳入 5428 例≥60 岁股骨颈无移位骨折患者。使用竞争风险分析估计各年龄组在 1、2 和 5 年内关节置换和死亡率的转化率。
1 年时关节置换的累积发生率函数(CIF)为 6.3%,2 年时为 8.1%,5 年时为 10.1%。2 年内的转化率为 60-69 岁为 6.5%,70-79 岁为 9.6%,≥80 岁为 7.8%。女性发生转化率的风险更高;风险比(HR)为 1.49(95%置信区间[CI],1.19 至 1.87)。1 年时累积死亡率为 21.3%(95%CI,20.3%至 22.5%),2 年时为 31.3%(95%CI,30.0%至 32.6%),5 年时为 54.9%(95%CI,53.1%至 56.7%)。所有时间点男性死亡率均较高,调整后的 1 年 HR 为 1.79(95%CI,1.61 至 2.00)。
≥60 岁股骨颈无移位骨折采用内固定治疗的患者中有 10%在 5 年内进行了关节置换,超过一半的转换发生在第 1 年内。女性和 70-79 岁患者的转化率最高。这些数据需要在这个脆弱的患者群体中进一步研究,以确定哪些亚组患者将从股骨颈无移位骨折的原发性关节置换中获益。
预后 III 级。有关证据水平的完整描述,请参见作者说明。