Choi Han-Gyo, Kim Hye-Jin
From the Digestive Disease Center, Samsung Medical Center, Seoul, Republic of Korea.
Department of Nursing, University of Ulsan, Ulsan, Republic of Korea.
Menopause. 2023 May 1;30(5):506-511. doi: 10.1097/GME.0000000000002092. Epub 2022 Nov 7.
The aim of this study was to present useful data for developing effective health management strategies for cardiovascular disease (CVD) prevention in postmenopausal women by investigating health-related behaviors and the prevalence of CVD for different types of obesity classified according to metabolic health status and body mass index criteria.
Using the 2016 Korean National Health and Nutrition Examination Survey VII-1 data, 1,190 menopausal women aged 50 years or older were analyzed in this cross-sectional study. The participants were divided into four groups as follows: metabolically healthy and normal weight (MHNW), metabolically obese but normal weight (MONW), metabolically healthy but obese, and metabolically obese and obese. Complex-samples general linear analysis, t tests, and logistic regression analysis were used to compare the differences in health-related behaviors and the risk of CVD among the four groups.
The risk for stroke was 3.61 times higher (95% CI, 1.18-11.03) in the MONW group than in the MHNW group.
We found a strong association between the MONW group of obesity and the risk for CVD, particularly stroke, in postmenopausal women. These findings would serve as valuable evidence for developing and implementing interventions to prevent stroke in postmenopausal women in the MONW group.
本研究旨在通过调查与健康相关的行为以及根据代谢健康状况和体重指数标准分类的不同类型肥胖的心血管疾病(CVD)患病率,为制定有效的绝经后女性心血管疾病预防健康管理策略提供有用数据。
利用2016年韩国国民健康与营养检查调查VII-1数据,在这项横断面研究中分析了1190名50岁及以上的绝经后女性。参与者被分为以下四组:代谢健康且体重正常(MHNW)、代谢性肥胖但体重正常(MONW)、代谢健康但肥胖以及代谢性肥胖且肥胖。采用复杂样本一般线性分析、t检验和逻辑回归分析来比较四组之间与健康相关行为的差异以及心血管疾病风险。
MONW组中风风险比MHNW组高3.61倍(95%CI,1.18 - 11.03)。
我们发现绝经后女性中,MONW型肥胖与心血管疾病风险,尤其是中风风险之间存在密切关联。这些发现将为制定和实施干预措施以预防MONW组绝经后女性中风提供有价值的证据。