补充单篇文章：儿科痤疮患者使用护肤品作为单一疗法、辅助疗法和维持疗法的真实世界病例系列

Supplement Individual Article: Pediatric Acne Patients' Treatment Real-World Case Series Using Skincare as Monotherapy, Adjunctive, and Maintenance Treatment.

出版信息

J Drugs Dermatol. 2023 Feb 1;22(2):SF376527s3-SF376527s14.

Abstract

BACKGROUND

Pediatric acne is a common, complex, multifactorial inflammatory skin disease with various expressions in childhood that can be categorized by age, severity, and pubertal status. A pediatric acne case series is presented to educate health care providers treating children with acne to tailor acne prescription, nonprescription acne therapy, skin care, and maintenance treatment to improve patient outcomes.

METHODS

A panel of 8 advisors in pediatric dermatology, dermatology, and pediatrics who treat pediatric patients with acne reported on clinical cases from their practice. During the meeting, the advisors discussed 17 pediatric acne cases and agreed to select 8 cases covering various presentations of pediatric acne, patient ages, and skin types. The case series gives a logical flow from youngest to oldest pediatric patients with acne.

RESULTS

The 8 cases covered neonatal acne: birth to ≤8 weeks; preadolescent acne: ≥7 to 12 years; and adolescent acne: ≥12 to 19 years or after menarche for girls. It is to be noted that acne eruptions in children ages 1 to 6 years old are unusual and often associated with underlying endocrine and tumor issues. They are not included in this work. The advisors discussed why they selected the case, previous treatment, type of prevention and education provided, skin care as mono or adjunctive treatment, prescription and nonprescription therapy and maintenance treatment, key takeaways, and clinical pearls from the case. Skincare products containing lipids such as ceramides promote a healthy skin barrier in acne monotherapy, adjunctive, and maintenance treatment. However, their role in pediatric acne is not well defined and requires more studies.

CONCLUSION

Sharing best practices in acne therapy and maintenance treatment for pediatric patients with acne may support health care providers treating children to improve clinical outcomes. J Drugs Dermatol. 2023;22:2(Suppl):s3-14.

摘要

背景

儿童痤疮是一种常见、复杂、多因素的炎症性皮肤病，在儿童期有多种表现形式，可根据年龄、严重程度和青春期状态进行分类。本文呈现了一组儿童痤疮病例，旨在教育治疗儿童痤疮的医护人员，使其能够根据痤疮情况调整处方、非处方痤疮治疗、皮肤护理和维持治疗方案，以改善患者治疗效果。

方法

一个由8名治疗儿童痤疮的儿科皮肤科、皮肤科和儿科顾问组成的小组报告了他们临床实践中的病例。会议期间，顾问们讨论了17例儿童痤疮病例，并同意选择8例涵盖儿童痤疮各种表现、患者年龄和皮肤类型的病例。该病例系列按痤疮患儿年龄从小到大进行了逻辑排列。

结果

这8个病例涵盖了新生儿痤疮（出生至≤8周）、青春期前痤疮（≥7至12岁）和青春期痤疮（≥12至19岁或女孩初潮后）。需要注意的是，1至6岁儿童出现痤疮皮疹并不常见，且常与潜在的内分泌和肿瘤问题相关。本研究未纳入此类病例。顾问们讨论了他们选择该病例的原因、既往治疗情况、提供的预防和教育类型、作为单一或辅助治疗的皮肤护理、处方和非处方治疗以及维持治疗、关键要点和该病例的临床经验。含神经酰胺等脂质的护肤品在痤疮单一疗法、辅助治疗和维持治疗中可促进健康的皮肤屏障。然而，它们在儿童痤疮中的作用尚不明确，需要更多研究。