Eryılmaz Ufuk, Sivri Fatih, Şencan Mehtap
Department of Cardiology, Adnan Menderes University, Aydın, Turkey.
Department of Cardiology, Hatay Dörtyol Hospital, Hatay, Turkey.
Postepy Kardiol Interwencyjnej. 2022 Sep;18(3):290-295. doi: 10.5114/aic.2022.120372. Epub 2022 Nov 2.
The increasing frequency of cardiac device use has led to an increase in complication rates. The standard treatment for cardiac device-related infections is removal of the entire pacemaker system and reimplantation from the contralateral side after systemic antibiotherapy. The efficacy of various conservative treatments has been established for many years, but there is conflicting information in the literature regarding long-term efficacy.
Our study investigated the long-term efficacy of conservative treatment in patients with pacemaker pocket site infection.
In this retrospective study, according to the exclusion criteria, 132 patients were included. Patients were divided into conservative and standard treatment groups. Conservative treatment was considered to be opening the pacemaker pocket capsule, removing all infected and necrotic tissue, cleaning the capsule, and embedding the battery in the prepectoral region in the subpectoral muscle region.
The follow-up time was 36 ±12.96 months in the conservative treatment group and 39.6 ±10.8 months in the standard treatment group. During this period, no re-infection at the pacemaker pocket site was observed in either group. Examination of the swab cultures of the patients' pacemaker wounds revealed negative culture results in 15 patients (15 out of 60) in the conservative treatment group. In the standard treatment group, 60 patients (60 out of 72) were culture-negative. This difference was statistically significant ( = 0.04).
After a rigorous evaluation, conservative treatment is considered effective and safe in the long term in patients with device pocket site infection.
心脏设备使用频率的增加导致并发症发生率上升。心脏设备相关感染的标准治疗方法是在全身抗生素治疗后,移除整个起搏器系统并从对侧重新植入。各种保守治疗的疗效已得到多年证实,但文献中关于长期疗效的信息存在冲突。
我们的研究调查了起搏器囊袋部位感染患者保守治疗的长期疗效。
在这项回顾性研究中,根据排除标准纳入了132例患者。患者被分为保守治疗组和标准治疗组。保守治疗被认为是打开起搏器囊袋,清除所有感染和坏死组织,清洁囊袋,并将电池埋入胸大肌区域的胸前区。
保守治疗组的随访时间为36±12.96个月,标准治疗组为39.6±10.8个月。在此期间,两组均未观察到起搏器囊袋部位再次感染。对患者起搏器伤口拭子培养物的检查显示,保守治疗组15例患者(60例中的15例)培养结果为阴性。在标准治疗组中,60例患者(72例中的60例)培养结果为阴性。这种差异具有统计学意义(P = 0.04)。
经过严格评估,保守治疗在长期来看对设备囊袋部位感染患者是有效且安全的。