Faculty of Medicine and University Hospital Cologne, Department of Orthopedics and Trauma Surgery, University of Cologne, Cologne, Germany.
Goethe-University Frankfurt, Department of Psychology, Frankfurt am Main, Germany.
Clin Orthop Relat Res. 2023 Aug 1;481(8):1610-1619. doi: 10.1097/CORR.0000000000002576. Epub 2023 Feb 13.
Spinal fusion is a well-established procedure in the treatment of degenerative spinal diseases. Previous research shows that the use of this operative treatment has been growing in recent decades in industrialized countries and has become one of the most cost-intensive surgical procedures. It seems that in some countries such as Germany-with its large, industrialized, European population-this increase is mainly driven by demographic changes with low fertility rates, increasing life expectancy, and an aging population. Based on current projections, however, Germany faces a population trend that many other countries are likely to follow within a few decades. An increasingly shrinking and aging working population may eventually put the healthcare system under enormous pressure, with greater demands for spinal fusions and associated higher costs. Thus, we aimed to provide reliable projections regarding the future demand for posterior spinal fusion procedures including age- and gender-related trends up to 2060, which will be necessary for future resource planning and possible improvements in actual treatment strategies.
QUESTIONS/PURPOSES: (1) How is the use of posterior spinal fusions in Germany expected to change from 2019 through 2060, if currents trends continue? (2) How is the use of posterior spinal fusions in Germany expected to change depending on patients' age and gender during this time period?
Comprehensive nationwide data provided by the Federal Statistical Office, the official institution for documenting all data on operations and procedures performed in Germany, were used to quantify posterior spinal fusion rates as a function of calendar year, age, and gender. Because there is a lack of evidence regarding future trends in the use of posterior spinal fusions, an autoregressive integrated moving average model on historical procedure rates from 2005 to 2019 in relation to official population projections from 2020 to 2060 was chosen to forecast future absolute numbers and incidence rates of this procedure in Germany. Long-term forecasting is more prone to unexpected disruptions than forecasting over short-term periods; however, longer spans facilitate estimates of how trends may challenge future healthcare systems if those trends continue, and thus are useful for research and planning.
The incidence rate of posterior spinal fusion was projected to increase by approximately 83% (95% CI 28% to 139%) to 102% per 100,000 inhabitants (95% CI 71% to 133%) in 2060, with a 1.3-fold higher rate of women undergoing surgery in terms of absolute numbers. The highest increase identified by the model occurred in patients 75 years and older with 38,974 (95% CI 27,294 to 50,653) posterior spinal fusions in 2060, compared with 14,657 in 2019. This trend applied for both women and men, with a 246% (95% CI 138% to 355%) increase in the total number of posterior spinal fusions for women 75 years and older and a 296% (95% CI 222% to 370%) increase for men 75 years and older. At the same time, posterior spinal fusions in all age groups younger than 55 years were projected to follow a constant or even negative trend up to 2060.
Our findings suggest that increasing use of posterior spinal fusion, particularly in patients 75 years and older, will challenge healthcare systems worldwide if current trends persist. This study may serve as a model for many other industrialized countries facing similar demographic and procedure-specific developments in the future. This emphasizes the need to focus on frailty research as well as appropriate financial and human resource management. Effective perioperative medical management, multidisciplinary treatment, and interinstitutional protocols are warranted, especially in older patients as we attempt to manage these trends in the future.
Level III, economic and decision analysis.
脊柱融合术是治疗退行性脊柱疾病的一种成熟手术。既往研究表明,近几十年来,在工业化国家,这种手术治疗的应用呈增长趋势,已成为最耗费医疗资源的手术之一。在德国这样的一些国家,其庞大的、工业化的、人口众多的欧洲人口基数,这种增长主要是由低生育率、预期寿命延长和人口老龄化等人口结构变化所驱动。然而,根据目前的预测,德国将面临一种人口趋势,在未来几十年内,许多其他国家可能也会出现这种情况。不断减少和老龄化的劳动人口最终可能会给医疗保健系统带来巨大压力,对脊柱融合术的需求增加,相关成本也会增加。因此,我们旨在提供关于未来脊柱后路融合术需求的可靠预测,包括到 2060 年与年龄和性别相关的趋势,这对于未来的资源规划和实际治疗策略的可能改进是必要的。
问题/目的:(1)如果延续当前趋势,德国 2019 年至 2060 年期间脊柱后路融合术的应用预计会如何变化?(2)在此期间,德国脊柱后路融合术的应用预计会如何因患者年龄和性别而变化?
利用联邦统计局提供的全面的全国性数据,该机构是记录德国所有手术和操作数据的官方机构,根据年龄和性别对脊柱后路融合率进行量化。由于缺乏关于未来脊柱后路融合术使用趋势的证据,我们选择了一个自回归综合移动平均模型,该模型基于 2005 年至 2019 年手术率与 2020 年至 2060 年官方人口预测之间的关系,对德国未来该手术的绝对数量和发生率进行预测。与短期预测相比,长期预测更容易受到意外干扰;然而,较长的预测跨度有助于估计如果这些趋势持续下去,它们可能会对未来的医疗保健系统构成的挑战,因此对于研究和规划是有用的。
预计到 2060 年,脊柱后路融合术的发病率将增加约 83%(95%CI 28%至 139%)至 102%(95%CI 71%至 133%),女性接受手术的绝对数量将增加 1.3 倍。模型确定的最高增幅发生在 75 岁及以上的患者中,2060 年将有 38974 例(95%CI 27294 例至 50653 例)脊柱后路融合术,而 2019 年为 14657 例。这一趋势适用于男性和女性,75 岁及以上女性的脊柱后路融合术总数将增加 246%(95%CI 138%至 355%),75 岁及以上男性的脊柱后路融合术总数将增加 296%(95%CI 222%至 370%)。与此同时,所有年龄组小于 55 岁的脊柱后路融合术预计将呈现出持续或甚至负增长的趋势,直至 2060 年。
如果当前趋势持续下去,我们的研究结果表明,脊柱后路融合术的使用不断增加,特别是在 75 岁及以上的患者中,将对全球医疗保健系统构成挑战。本研究可以作为许多其他面临类似人口和特定手术发展的工业化国家的模型。这强调了需要关注脆弱性研究以及适当的财务和人力资源管理。需要进行有效的围手术期医疗管理、多学科治疗和机构间协议,特别是在老年患者中,我们试图在未来管理这些趋势。
三级,经济和决策分析。