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经巩膜睫状体腔注射曲安奈德治疗抵抗性糖尿病黄斑水肿。

Suprachoroidal injection of triamcinolone acetonide for management of resistant diabetic macular oedema.

机构信息

Department of Ophthalmology, Isra Postgraduate Institute of Ophthalmology, Karachi, Pakistan.

Department of Ophthalmology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2023 Feb;73(2):239-244. doi: 10.47391/JPMA.2239.

Abstract

OBJECTIVE

To estimate the effects and safety of suprachoroidal triamcinolone acetonide injections in treating patients with resistant diabetic macular oedema.

METHODS

The quasi-experimental study was conducted at the Isra Postgraduate Institute of Ophthalmology, Al-Ibrahim Eye Hospital, Karachi, from November 2019 to March 2020, and adult patients of either gender with uncontrolled diabetes mellitus. Central macular thickness, intraocular pressure and best corrected visual acuity were recorded at baseline, and the patients were followed up at one and three months after the suprachoroidal triamcinolone acetonide injection and post-intervention parameters were compared. Data was analysed using SPSS 20.

RESULTS

There were 60 patients with a mean age of 49.25±5.6 years. Of the 70 eyes, 38(54.30%) belonged to male subjects and 32(45.70%) to female subjects. There were significant differences in terms of central macular thickness and the best corrected visual acuity at both follow-ups compared to the baseline readings (p<0.05).

CONCLUSIONS

Suprachoroidal triamcinolone acetonide injection significantly reduced diabetic macular oedema.

摘要

目的

评估玻璃体内曲安奈德注射治疗耐药性糖尿病黄斑水肿患者的效果和安全性。

方法

本准实验研究于 2019 年 11 月至 2020 年 3 月在卡拉奇的以色列眼科研究生学院、易卜拉欣眼科医院进行,纳入的研究对象为未得到控制的糖尿病成年患者,无论性别。在基线时记录中央黄斑厚度、眼内压和最佳矫正视力,在玻璃体内曲安奈德注射后 1 个月和 3 个月进行随访,并比较干预后的参数。采用 SPSS 20 进行数据分析。

结果

共有 60 名平均年龄为 49.25±5.6 岁的患者纳入研究。在 70 只眼中,38 只(54.30%)眼为男性,32 只(45.70%)眼为女性。与基线读数相比,在两次随访时中央黄斑厚度和最佳矫正视力均有显著差异(p<0.05)。

结论

玻璃体内曲安奈德注射显著减轻了糖尿病黄斑水肿。

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