Rafal R D, Inhoff A W, Friedman J H, Bernstein E
Division of Neurology, Roger Williams General Hospital, Providence, RI 02908.
J Neurol Neurosurg Psychiatry. 1987 Oct;50(10):1267-73. doi: 10.1136/jnnp.50.10.1267.
In separate blocks of a simple reaction time (RT) task, eight Parkinsonian and eight control subjects executed finger press sequences with one (index finger), two (index finger-ring) or three (index finger-ring-middle) components. Programming was inferred from the increase latency to initiate the first component as a function of the length of the entire sequence; and from the systematic decrease in inter-response latencies for the second and third components. Overall RT was slower in the Parkinsonians but the programming effects were comparable in the two groups. Intact basal ganglia function appears not to be necessary for programming sequential finger movements, or retrieving subprograms for execution.
在简单反应时间(RT)任务的不同组块中,8名帕金森病患者和8名对照受试者用一根手指(食指)、两根手指(食指-无名指)或三根手指(食指-无名指-中指)执行按键序列。通过将启动第一个成分的延迟增加作为整个序列长度的函数来推断编程;并通过第二个和第三个成分的反应间延迟的系统性减少来推断编程。帕金森病患者的总体反应时间较慢,但两组的编程效应相当。完整的基底神经节功能似乎对于编程连续的手指运动或检索要执行的子程序并非必要。