Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Tianjin Medical University, Tianjin, China.
J Med Case Rep. 2023 Feb 22;17(1):80. doi: 10.1186/s13256-022-03733-9.
Neurocysticercosis is a parasitic infection of the central nervous system by tapeworm larvae. Spinal cysticercosis is thought to be relatively rare, and spinal nerve root sleeve cysticercosis have not been reported previously.
A 46-year-old Chinese Han female patient presented with low back pain and radicular pain of the right lower limb. The visual analog scale was 6. Magnetic resonance imaging showed a subarachnoid cyst at the S1 level, with a slight enhanced rim. The patient underwent surgical treatment. During surgery, we found the cyst located mainly in the subarachnoid space and partly in a sacral nerve root sleeve. Cysticercosis was also confirmed by postoperative pathological examination. Postoperative drug therapy was performed after cysticercosis was confirmed. Postoperatively, the patient was treated with oral albendazole (15 mg/kg) for 1 month. Only mild sensory impairment was left when she was discharged. After 3 years of follow-up, the visual analog scale reduced from 6 to 2, and the patient's sensory function completely recovered. Magnetic resonance imaging showed no recurrence of cysticercosis.
Subarachnoid cysticercosis may extend to nerve root sleeve causing back pain and radiculopathy, which may present with similar magnetic resonance imaging manifestations to Tarlov cysts. Hence, spinal subarachnoid cysticercosis should be considered as an important differential diagnosis of arachnoid cyst and sacral Tarlov cyst. Combined treatment with surgical removal and drug therapy is effective to manage spinal subarachnoid cysticercosis.
神经囊尾蚴病是一种由绦虫幼虫引起的中枢神经系统寄生虫感染。脊髓囊尾蚴病被认为相对罕见,以前没有报道过脊髓神经根袖囊尾蚴病。
一名 46 岁的汉族女性患者出现腰痛和右下肢神经根痛,视觉模拟评分(VAS)为 6 分。磁共振成像(MRI)显示 S1 水平蛛网膜下腔有一个边缘轻微增强的囊肿。患者接受了手术治疗。术中发现囊肿主要位于蛛网膜下腔,部分位于骶神经根袖内。术后病理检查证实为囊尾蚴病。在确认囊尾蚴病后进行了药物治疗。术后给予口服阿苯达唑(15mg/kg)治疗 1 个月。患者出院时仅遗留轻度感觉障碍。随访 3 年后,VAS 从 6 降至 2,患者的感觉功能完全恢复。MRI 显示无囊尾蚴病复发。
蛛网膜下腔囊尾蚴病可能延伸至神经根袖,引起背痛和神经根病,其磁共振成像表现可能与 Tarlov 囊肿相似。因此,脊髓蛛网膜下腔囊尾蚴病应作为蛛网膜囊肿和骶骨 Tarlov 囊肿的重要鉴别诊断。手术切除联合药物治疗对管理脊髓蛛网膜下腔囊尾蚴病有效。