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一名35岁女性因卵巢透明细胞癌继发右大脑中动脉卒中:病例报告

Right middle cerebral artery stroke secondary to ovarian clear cell carcinoma in a 35-year-old: A case report.

作者信息

Blustein Pegah, Werner Sarah, Sham Sunder, Febles Anthony, Katz Heather, Villella Jeannine

机构信息

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Blvd, Hempstead, NY 11549, United States.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology Lenox Hill Hospital, 100 E 77 St, New York, NY 10075, United States.

出版信息

Case Rep Womens Health. 2023 Feb 10;37:e00485. doi: 10.1016/j.crwh.2023.e00485. eCollection 2023 Mar.

Abstract

Thromboembolic events (TEEs) can be classified into two types: venous TEEs (vTEEs), such as pulmonary embolism (PE) and deep vein thrombosis (DVT), and arterial TEEs (ATEs), such as acute myocardial infarction and cerebral infarction. Ovarian cancer has a high incidence of venous thromboembolism, with the clear cell subtype carrying the highest risk. However, the incidence of ATEs, especially cerebral infarction, in patients with ovarian carcinoma, of all subtypes, is much lower. This report is of a rare case of a 35-year-old Asian woman who presented with sudden onset of left hemiplegia and right gaze as the first presenting signs of an underlying ovarian malignancy. The patient had no pertinent medical history and no underlying cardiovascular risk factors. Final diagnosis was stage 2B clear cell carcinoma of the ovary without lymphovascular invasion arising from endometriosis. Patients who suffer from arterial thrombosis without known atherosclerotic risk factors should undergo further evaluations to rule out the possibility of cancer, particularly ovarian carcinoma.

摘要

血栓栓塞事件(TEEs)可分为两种类型:静脉血栓栓塞事件(vTEEs),如肺栓塞(PE)和深静脉血栓形成(DVT),以及动脉血栓栓塞事件(ATEs),如急性心肌梗死和脑梗死。卵巢癌发生静脉血栓栓塞的几率很高,其中透明细胞亚型风险最高。然而,在所有亚型的卵巢癌患者中,动脉血栓栓塞事件,尤其是脑梗死的发生率要低得多。本报告介绍了一例罕见病例,一名35岁的亚洲女性,最初表现为突然出现左侧偏瘫和向右凝视,这是潜在卵巢恶性肿瘤的首发症状。该患者无相关病史,也无潜在心血管危险因素。最终诊断为卵巢2B期透明细胞癌,起源于子宫内膜异位症,无淋巴血管侵犯。患有动脉血栓形成且无已知动脉粥样硬化危险因素的患者应接受进一步评估,以排除癌症尤其是卵巢癌的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3881/9938153/6eb142bd7011/gr1.jpg

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