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在叶片建模优化后,为 VMAT 计划实现有效且优化的特定于患者的 QA 工作量减少。

An effective and optimized patient-specific QA workload reduction for VMAT plans after MLC-modelling optimization.

机构信息

Medical Physics Department, Institut de Cancréologie de l'Ouest, Bd du Professeur Jacques Monod, 44805 Saint Herblain Cedex, France.

Medical Physics Department, Institut de Cancréologie de l'Ouest, Rue André Bocquel, 49055 Angers, France.

出版信息

Phys Med. 2023 Mar;107:102548. doi: 10.1016/j.ejmp.2023.102548. Epub 2023 Feb 24.

Abstract

INTRODUCTION

Many complexity metrics characterize modulated plans. First, this study aimed at identify the optimal complexity metrics to reduce workload associated to patient-specific quality assurance (PSQA) for our equipment and processes. Second, it intended to optimize our MLC modelling to improve measurement and calculation agreement with expectation of further reducing PSQA workload.

METHODS

Correlation and sensitivity at specificity equals to 1 were evaluated for PSQA results and different complexity metrics. Thresholds to stop PSQA were determined. After validation of the optimal complexity metric and threshold for our equipment and process, the MLC modelling was reviewed with a recently published methodology. This method is based on measurements with a Farmer-type ionization chamber of synchronous and asynchronous sweeping gap plans. Effect on the PSQA results and the identified threshold was investigated.

RESULTS

In our center, the most appropriate complexity metric for reducing our PSQA workload was the Modulation Complexity Score for VMAT (MCSv). The optimization of the MLC modelling significantly reduced the number of controlled plans, specifically for one of our two Varian Clinac. Any plan with a MCSv >= 0.34 is treated without PSQA.

CONCLUSION

This study rationalized and reduced our PSQA workload by approximately 30%. It is a continuing work with new TPS, machine or PSQA equipment. It encourages centers to re-evaluate their MLC modelling as well as assess the benefit of complexity metrics to streamline their PSQA workflow. An easier access, at least for reporting, at best for optimizing plans, into the TPS would be beneficial for the community.

摘要

简介

许多复杂性指标可用于描述调制计划。首先,本研究旨在确定最佳的复杂性指标,以降低我们设备和流程的特定于患者的质量保证(PSQA)相关的工作量。其次,它旨在优化我们的 MLC 建模,以提高与预期的测量和计算一致性,从而进一步降低 PSQA 工作量。

方法

评估 PSQA 结果和不同复杂性指标之间的相关性和特异性等于 1。确定停止 PSQA 的阈值。在验证了我们设备和流程的最佳复杂性指标和阈值后,采用最近发表的方法对 MLC 建模进行了审查。该方法基于使用 Farmer 型电离室对同步和异步扫隙计划进行测量。研究了对 PSQA 结果和确定的阈值的影响。

结果

在我们中心,降低 PSQA 工作量的最合适的复杂性指标是 VMAT 的调制复杂性评分(MCSv)。MLC 建模的优化显著减少了受控计划的数量,特别是对于我们的两台 Varian Clinac 之一。任何 MCSv>=0.34 的计划都无需进行 PSQA。

结论

本研究通过大约 30%的工作量合理化和减少了我们的 PSQA 工作量。这是一项与新的 TPS、机器或 PSQA 设备持续进行的工作。它鼓励中心重新评估他们的 MLC 建模,并评估复杂性指标对简化其 PSQA 工作流程的益处。至少在报告方面,最好是在优化计划方面,更方便地访问 TPS 将有益于社区。

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