源自红树林的sp. SCSIO 40069中的芳香族聚酮化合物。
Aromatic Polyketides from the Mangrove-Derived sp. SCSIO 40069.
作者信息
Sun Lili, Zhu Hanning, Zhang Liping, Zhu Yiguang, Ratnasekera Disna, Zhang Changsheng, Zhang Qingbo
机构信息
Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
出版信息
J Nat Prod. 2023 Apr 28;86(4):979-985. doi: 10.1021/acs.jnatprod.2c01169. Epub 2023 Mar 15.
A chemical investigation of sp. SCSIO 40069 resulted in the isolation of a series of aromatic polyketides with rare skeletons, including five new compounds RM18c-RM18g (-) and three known ones (-). Their structures and absolute configurations were determined by diverse methods, including HRMS and NMR spectra, chemical reaction, Snatzke's method, quantum mechanical-nuclear magnetic resonance (QM-NMR), and X-ray crystallographic analysis. Compounds , , , and displayed moderate or weak antibacterial activities.
对菌株SCSIO 40069进行化学研究，分离得到了一系列具有罕见骨架的芳香族聚酮化合物，包括5个新化合物RM18c - RM18g（-）和3个已知化合物（-）。通过多种方法确定了它们的结构和绝对构型，这些方法包括高分辨质谱（HRMS）和核磁共振光谱（NMR）、化学反应、施纳茨克方法、量子力学 - 核磁共振（QM - NMR）以及X射线晶体学分析。化合物 、 、 和 表现出中等或较弱的抗菌活性。
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