终止高血压膳食方法（DASH）饮食与2019冠状病毒病患者住院风险的关联。
The association of dietary approach to stop hypertension (DASH) diet with hospitalization risk in patients with COVID-19.
作者信息
Zamanian Ali, Yari Zahra, Soltanieh Samira, Salavatizadeh Marieh, Karimi Sara, Ardestani Sussan K, Salehi Mohammadreza, Jahromi Soodeh Razeghi, Ghazanfari Tooba, Hekmatdoost Azita
机构信息
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Science, Tehran, Iran.
Department of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Clin Nutr Open Sci. 2023 Apr;48:55-63. doi: 10.1016/j.nutos.2023.02.001. Epub 2023 Mar 5.
BACKGROUND AND AIM
Given the importance of dietary habits in the immune system, the current study aimed at investigating the association between Dietary Approach to Stop Hypertension (DASH) diet and risk of hospitalization due to COVID-19.
METHODS
Dietary data of 141 patients with COVID-19 were collected using 147-item food frequency questionnaire. DASH score in this cross-sectional study was calculated based on eight components, including fruits, vegetables, legumes and nuts and seeds, whole grains, low-fat dairy, red or processed meats, sweetened beverages, and sodium. Multivariable logistic regression models were applied to estimate the OR and 95% CI for hospitalization due to COVID-19 in each tertile of DASH score.
RESULTS
Mean ± SD of DASH score in inpatients (n=74) and outpatients (n= 87) was 22.5 ± 4.57 and 25.34 ± 4.23, respectively. The risk of hospitalization in the highest tertile of DASH score was 81% lower than the lowest tertile (OR=0.19, 95%CI: 0.07-0.55, trend = 0.001 after adjustment for age, sex, BMI, energy intake). Also, more intake of fruits, vegetables and low-fat dairy products and less intake of sodium, red and processed meat were each significantly associated with reduced risk of hospitalization due to COVID-19.
CONCLUSIONS
Our data provide evidence that adherence to DASH-style diet was associated with lower risk of hospitalization due to COVID-19.
背景与目的
鉴于饮食习惯对免疫系统的重要性，本研究旨在调查终止高血压膳食疗法（DASH）饮食与因2019冠状病毒病（COVID-19）住院风险之间的关联。
方法
使用包含147个条目的食物频率问卷收集了141例COVID-19患者的饮食数据。在这项横断面研究中，DASH评分基于八个组成部分计算得出，包括水果、蔬菜、豆类、坚果和种子、全谷物、低脂乳制品、红肉或加工肉类、含糖饮料和钠。应用多变量逻辑回归模型来估计DASH评分各三分位数中因COVID-19住院的比值比（OR）和95%置信区间（CI）。
结果
住院患者（n = 74）和门诊患者（n = 87）的DASH评分均值±标准差分别为22.5±4.57和25.34±4.23。DASH评分最高三分位数的住院风险比最低三分位数低81%（OR = 0.19，95%CI：0.07 - 0.55，调整年龄、性别、体重指数、能量摄入后趋势 = 0.001）。此外，水果、蔬菜和低脂乳制品摄入量增加以及钠、红肉和加工肉类摄入量减少均与因COVID-19住院风险降低显著相关。
结论
我们的数据提供了证据，表明坚持DASH式饮食与因COVID-19住院风险较低相关。
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